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N-Acetyl-L-cysteine CAS:616-91-1
N-Acetyl-L-cysteine (NAC) ke mofuta o fetotsoeng oa amino acid cysteine. E fana ka mohloli oa cysteine 'me e ka fetoloa habonolo ho ba tripeptide glutathione, antioxidant e matla' meleng. NAC e tsebahala ka thepa ea eona ea antioxidant le mucolytic, e leng se etsang hore e be molemo lits'ebetsong tse fapaneng tsa bophelo bo botle.
Jwalo ka antioxidant, NAC e thusa ho sireletsa disele tshenyong e bakwang ke di-free radicals, mefuta ya oksijene e arabelang, le chefo. E boetse e tshehetsa tlhahiso ya glutathione, e bapalang karolo ya bohlokwa mekgweng ya ho ntsha chefo mmeleng le ho boloka sesole sa mmele se phetseng hantle.
NAC e ithutiloe bakeng sa melemo ea eona e ka bang teng bophelong bo botle ba ho hema, haholo-holo bakeng sa batho ba nang le maemo a kang bronchitis e sa foleng, COPD le cystic fibrosis. Hangata e sebelisoa e le setlolo sa ho ntša metsi ho thusa ho tšesa le ho lokolla mucus, e leng se etsang hore ho be bonolo ho hloekisa litsela tsa ho hema.
Ho feta moo, NAC e bontšitse tšepiso ea ho tšehetsa bophelo bo botle ba sebete ka ho thusa ho tlosa lintho tse chefo, tse kang acetaminophen, e leng moriana o tloaelehileng oa bohloko. E ka boela ea ba le litlamorao tse sireletsang khahlanong le tšenyo ea sebete e bakoang ke ho noa joala.
Ntle le thepa ea eona ea antioxidant le tšehetso ea ho hema, NAC e 'nile ea hlahlojoa bakeng sa melemo ea eona e ka bang teng bophelong ba kelello. Lipatlisiso tse ling li bontša hore e ka ba le tšusumetso e ntle mathateng a maikutlo, a kang khatello ea maikutlo le bothata ba ho qobella ho hema (OCD).
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GLYCYL-L-PROLINE CAS: 704-15-4
Glycyl-L-proline, e tsejoang hape e le glycylproline kapa Gym-Pro, ke motsoako oa amino acid o entsoeng ka amino acid glycine e hoketsoeng ho amino acid L-proline. Ke motsoako o hlahang ka tlhaho o fumanoang ka har'a collagen, protheine e ikarabellang bakeng sa sebopeho le matla a lisele tse fapaneng 'meleng. Glycyl-L-proline e 'nile ea ithutoa ka melemo ea eona ea bophelo bo botle, ho kenyeletsoa ho khothaletsa bophelo bo botle ba letlalo, ho fokotsa ho ruruha, le ho tšehetsa bophelo bo botle ba manonyello le masapo. E boetse e sebelisoa mefuteng ea litlolo bakeng sa thepa ea eona ea ho nolofatsa le ho thibela ho bola ha letlalo.
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Guanidine Hydrochloride CAS:50-01-1
Guanidine hydrochloride ke motsoako oa lik'hemik'hale o nang le foromo ea limolek'hule ea CH5N3·HCl. Ke sesebelisoa se matla sa chaotropic se sebelisoang haholo lits'ebetsong tsa biochemistry le baeloji ea limolek'hule.
Guanidine hydrochloride e atisa ho sebelisoa ho fokotsa liprotheine, ho sitisa mehaho ea protheine, le ho bula liprotheine bakeng sa merero ea tlhoekiso. E sebetsa haholo-holo ho robeng maqhama a haeterojene le ho sitisa likamano tse seng tsa covalent ka har'a liprotheine. Thepa ena e etsa hore e be molemo bakeng sa ho qhibilihisa liprotheine tseo hangata li sa qhibiliheng kapa li sekametseng ho kopana.
E boetse e sebelisoa e le sesebelisoa sa ho tsitsisa protheine, e sireletsa liprotheine ho tsoa ho kopaneng ho sa batleheng kapa ho senyeha ha tlhaho nakong ea liteko tse fapaneng tsa biochemical le biophysical. Guanidine hydrochloride e ka thusa ho boloka sebopeho sa tlhaho le ts'ebetso ea liprotheine tlas'a maemo a ho fetoha ha tlhaho..
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Acetylthiocholine iodide CAS:1866-15-5
Acetylthiocholine iodide ke motsoako oa lik'hemik'hale o atisang ho sebelisoa e le substrate litekong tsa enzyme ho lekanya mosebetsi oa enzyme acetylcholinesterase (AChE). AChE ke enzyme e haellang acetylcholine ea neurotransmitter, e leng mohato oa bohlokoa oa ho felisa phetiso ea lets'oao lipakeng tsa lisele tsa methapo.
Ha acetylthiocholine iodide e sebetsoa ke AChE, sehlopha sa acetyl sea tlosoa, e leng se fellang ka ho thehwa ha thiocholine le acetate ions. Thiocholine e ntan'o arabela ka reagent e se nang 'mala e bitsoang DTNB (5,5′-dithiobis (2-nitrobenzoic acid)) ho hlahisa motsoako o mosehla o bitsoang 5-thio-2-nitrobenzoate, o ka lekanngoang ka spectrophotometric. Sekhahla sa ntshetsopele ya mmala se lekana ka ho toba le mosebetsi wa AChE sampole.
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2-Methoxy-4-morpholinobenzenediazonium chloride zinki chloride letsoai le habeli (21) CAS: 67801-08-5
2-Methoxy-4-morpholinobenzenediazonium chloride zinc chloride letswai le habeli ke motsoako o tiileng oa kristale o sebelisoang e le reagent ho tsoakoeng ea lintho tse phelang. O na le diazonium cation, li-anion tsa chloride, le li-cation tsa zinc. Motsoako ona o fana ka botsitso bo ntlafalitsoeng le ho qhibiliha, e leng se etsang hore o lokele lits'ebetso tse fapaneng tsa lik'hemik'hale le meriana.
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4,5-Diazafluoren-9-one CAS:50890-67-0
4,5-Diazafluoren-9-one ke motsoako oa lik'hemik'hale o leng oa sehlopha sa metsoako ea aromatic ea heterocyclic. E entsoe ka masapo a fluorene a nang le liathomo tse peli tsa naetrojene (diaza) le athomo ea oksijene (e le 'ngoe) e khomaretsoeng libakeng tse itseng. E sebelisoa hangata e le motheo oa kaho kapa bohareng ba motsoako oa lintho tse phelang, haholo-holo ha ho lokisoa metsoako e fapaneng ea lintho tse phelang, meriana le dae. Sebopeho sa eona le karabelo ea eona li etsa hore e be sesebelisoa sa bohlokoa bakeng sa ho theha meaho e fapaneng ea limolek'hule le lihlopha tse sebetsang.
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Tapso Sodium CAS: 105140-25-8 Theko ea moetsi
3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid,Ke 'nasa zwitterionic buffering agent ka sebopeho sa letsoai la sodium. E sebelisoa hangata litekong tsa biochemical le tsa baeloji ea limolek'hule bakeng sa ho boloka pH e tsitsitseng litharollong.It E qhibiliha haholo metsing 'me e na le pKa e haufi le pH ea fisioloji, e leng se etsang hore e lokele mefuta e mengata ea lits'ebetso tse kang tlhoekiso ea protheine, liteko tsa enzyme, setso sa sele le electrophoresis. Sebopeho sa eona se ikhethang sa lik'hemik'hale le ho lumellana ha eona le litsamaiso tsa baeloji ho etsa hore e be karolo ea bohlokoa liprothokholong tse fapaneng tsa laboratori.
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Letswai la 4-Nitrophenyl phosphate di(tris) CAS:68189-42-4
Letswai la 4-Nitrophenyl phosphate di(tris) ke motsoako wa dikhemikhale o sebediswang dipatlisisong tsa dikhemikhale le dihlahlobong. Hangata le sebediswa e le substrate bakeng sa diteko tsa alkaline phosphatase enzyme. Letswai lena, ha le hydrolyzed ke alkaline phosphatase, le hlahisa sehlahisoa se mmala o mosehla se ka lekanngwang habonolo ka spectrophotometric. Karabelo ena e sebediswa haholo dikopong tse fapaneng, ho kenyeletswa diteko tsa immunosorbent tse amanang le enzyme (ELISAs) le ho lemoha mesebetsi ya phosphatase. Matla a mmala o mosehla a lekana ka ho toba le mosebetsi wa enzyme, e leng se dumellang ho lekanya ka nepo maemo a alkaline phosphatase disampoleng tsa baeloji. Letswai la 4-Nitrophenyl phosphate di(tris) le tsitsitse, le qhibiliha metsing, mme le na le kutlo e matla haholo, e leng se etsang hore e be kgetho e tsebahalang bakeng sa diteko tsa enzyme dipatlisisong tsa baeloji le tsa bongaka.
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Nitrotetrazolium blue chloride CAS:298-83-9
Nitrotetrazolium blue chloride, e tsejoang hape e le NBT kapa NBT-Cl, ke motsoako oa lik'hemik'hale o sebelisoang haholo litekong tsa baeloji le tsa biochemical. Ke phofo e kristale e mosehla o moputsoa e qhibilihang ka metsing.
NBT e sebediswa kgafetsa e le sesupo sa ho lemoha boteng ba di-radical tsa superoxide kapa di-enzyme tse di hlahisang. E fetoha mmala ha e fokotswa ke di-radical tsa superoxide, e fetoha ho tloha bosehla ho ya ho boputswa bo tebileng ba formazan. Karabelo ena hangata e sebediswa ditekong tsa ho ithuta kgatello ya oxidative, ho hema ha sele, le mosebetsi wa di-enzyme.
NBT e atisa ho sebelisoa mekhoeng e fapaneng, joalo ka ho fokotsa nitroblue tetrazolium, ho bona tlhahiso ea superoxide liseleng le liseleng. E boetse e sebelisitsoe ho immunohistochemistry le histochemistry ho lemoha le ho fumana li-enzyme tse ling le likarolo tsa sele.
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NSP-AS CAS:211106-69-3 Theko ea moetsi
Letswai la kahare la 3-[9-((3-(carboxypropyl)[4-Methxylphenyl]sulfonyl)aMine)carboxyl]-10-acridiniuMyl)-1-propanesulfonate ke molek'hule e rarahaneng e nang le karolo ea acridinium e hoketsoeng letswai la kahare la propanesulfonate. E na le sehlopha sa carboxypropyl, sehlopha sa 4-Methxylphenylsulfonyl, le sehlopha sa amine. Motswako ona ho ka etsahala hore o entswe bakeng sa ditshebediso tse itseng dibakeng tse kang k'hemistri, meriana, kapa dipatlisiso.
Ho feta moo, NAC e bontšitse tšepiso ea ho tšehetsa bophelo bo botle ba sebete ka ho thusa ho tlosa lintho tse chefo, tse kang acetaminophen, e leng moriana o tloaelehileng oa bohloko. E ka boela ea ba le litlamorao tse sireletsang khahlanong le tšenyo ea sebete e bakoang ke ho noa joala.
Ntle le thepa ea eona ea antioxidant le tšehetso ea ho hema, NAC e 'nile ea hlahlojoa bakeng sa melemo ea eona e ka bang teng bophelong ba kelello. Lipatlisiso tse ling li bontša hore e ka ba le tšusumetso e ntle mathateng a maikutlo, a kang khatello ea maikutlo le bothata ba ho qobella ho hema (OCD).
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L-Leucine p-nitroanilide hydrochloride CAS:16010-98-3
L-Leucine p-nitroanilide hydrochloride ke motsoako oa lik'hemik'hale o leng sehlopheng sa li-derivatives tsa p-nitroanilide. Ke phofo ea kristale e tšoeu ho isa ho e tšoeu e sebelisoang hangata lipatlisisong tsa biochemical le litekong tsa enzyme.
Hangata L-Leucine p-nitroanilide hydrochloride e sebediswa e le substrate ho lekanya tshebetso ya dienzyme tse kang diprotheine le di-peptidase. Ha dienzyme tsena di arola L-Leucine p-nitroanilide hydrochloride, e lokolla p-nitroaniline, e ka bonwang ka spectrophotometric. Sekgahla sa phetoho ya mmala se tsamaellana ka ho toba le mosebetsi wa enzymatic, e leng se dumellang ho lekanngwa ha mosebetsi wa enzymatic disampoleng tsa baeloji.
Motsoako ona o qhibiliha ka metsing 'me o ka qhibiliha habonolo litharollong tse loketseng tsa buffer bakeng sa tšebeliso litekong tsa enzymatic. Ho bohlokoa ho boloka L-Leucine p-nitroanilide hydrochloride sebakeng se pholileng le se omileng ho boloka botsitso ba eona.
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Guanidine Thiocyanate Sulfate CAS:593-84-0
Guanidine thiocyanate sulfate ke motsoako oa lik'hemik'hale o nkiloeng ho li-ion tsa guanidine, thiocyanate, le sulfate. E sebelisoa hangata lipatlisisong tsa baeloji ea limolek'hule le biochemistry e le moemeli oa chaotropic.
Guanidine thiocyanate sulfate hangata e sebediswa diprotheineng tsa ho arola DNA le RNA ho sitisa lera la sele le diprotheine tse qhibilihisitsweng, e leng se dumellang ho ntshwa ha di-nucleic acid ka katleho. E thusa ho qhibilihisa DNA le RNA, e nolofalletsang ho arolwa le ho hlwekiswa ha tsona disampoleng tse fapaneng tsa baeloji.
Ka lebaka la thepa ea eona ea chaotropic, guanidine thiocyanate sulfate e thusa ho roba khokahano ea haedrojene le likamano tse ling tse seng tsa covalent, e nolofalletsa karohano ea li-nucleic acid ho liprotheine, lipids le likarolo tse ling tsa sele. E boetse e thusa ho thibela ts'ebetso ea RNase, ho netefatsa botšepehi le bohloeki ba li-nucleic acid tse ntšitsoeng..
