Acetylthiocholine iodide CAS:1866-15-5

Acetylthiocholine iodide ke motsoako oa lik'hemik'hale o atisang ho sebelisoa e le substrate litekong tsa enzyme ho lekanya mosebetsi oa enzyme acetylcholinesterase (AChE). AChE ke enzyme e haellang acetylcholine ea neurotransmitter, e leng mohato oa bohlokoa oa ho felisa phetiso ea lets'oao lipakeng tsa lisele tsa methapo.

Ha acetylthiocholine iodide e sebetsoa ke AChE, sehlopha sa acetyl sea tlosoa, e leng se fellang ka ho thehwa ha thiocholine le acetate ions. Thiocholine e ntan'o arabela ka reagent e se nang 'mala e bitsoang DTNB (5,5′-dithiobis (2-nitrobenzoic acid)) ho hlahisa motsoako o mosehla o bitsoang 5-thio-2-nitrobenzoate, o ka lekanngoang ka spectrophotometric. Sekhahla sa ntshetsopele ya mmala se lekana ka ho toba le mosebetsi wa AChE sampole.

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Tšebeliso le Phello

Tekanyo ea ts'ebetso ea acetylcholinesterase (AChE): Acetylthiocholine iodide e sebelisoa hangata e le substrate litekong tsa enzyme ho lekanya ts'ebetso ea AChE. AChE ke enzyme e haellang acetylcholine ka metsi, 'me ka ho lekanya ts'ebetso ea eona, bafuputsi ba ka hlahloba ts'ebetso ea cholinergic le litlamorao tsa lithethefatsi, chefo, kapa mafu ho AChE.

Sesebelisoa sa ho hlahloba mafu a methapo ea kutlo: Ho se sebetse hantle ha AChE ho bonoa mafung a 'maloa a methapo ea kutlo, ho kenyeletsoa le lefu la Alzheimer's. Ho lekanya mosebetsi oa AChE ho sebelisoa acetylthiocholine iodide ho ka thusa ho hlahloba le ho beha leihlo mafu a joalo.

Lithuto tsa Chefo: Acetylthiocholine iodide e boetse e sebelisoa lithutong tsa chefo ho lekola litlamorao tsa lik'hemik'hale kapa chefo mosebetsing oa AChE. Lik'hemik'hale tse ling, tse kang organophosphate le carbamate insecticides, li ka thibela mosebetsi oa AChE, e leng se lebisang liphellong tse chefo. Acetylthiocholine iodide e ka fana ka temohisiso mabapi le chefo le mekhoa ea ts'ebetso ea metsoako ena.

Tlhahlobo bakeng sa li-inhibitor tsa AChE: Acetylthiocholine iodide e sebelisoa ho sibolleng le ho nts'etsopele ea meriana ho hlahloba le ho khetholla li-inhibitor tse ka bang teng tsa AChE. Li-inhibitor tsa AChE li ka ba molemo kalafong ea maemo a fapaneng, ho kenyeletsoa le lefu la Alzheimer's.

Nts'etsopele ea li-biosensor: Acetylthiocholine iodide, hammoho le AChE, e sebelisoa nts'etsopele ea li-biosensor bakeng sa ho lemoha acetylcholine. Li-biosensor tsena li fumana lits'ebetso libakeng tse kang tlhokomelo ea tikoloho le tlhahlobo ea bongaka.

Ho paka Sehlahisoa:

Tlhahisoleseling e 'Ngoe:

Sebopeho	C7H16INOS
Teko	99%
Ponahalo	Phofo e tšoeu
Nomoro ea CAS	1866-15-5
Ho paka	E nyane le e ngata
Bophelo ba Shelofo	lilemo tse 2
Polokelo	Boloka sebakeng se pholileng le se omileng
Setifikeiti	ISO.