Wortmannin CAS:19545-26-7 Theko ea moetsi

Wortmannin ke motsoako oa lik'hemik'hale o hlahang ka tlhaho o sebelisoang hangata lipatlisisong tsa laboratori ho ithuta lits'ebetso tse fapaneng tsa sele. Ke thibelo e matla ea phosphoinositide 3-kinase (PI3K), e leng enzyme e amehang litseleng tse fapaneng tsa lipontšo ka har'a lisele.

Ka ho thibela PI3K, wortmannin e ka thibela ka katleho ts'ebetso ea limolek'hule tsa lipontšo tse theohelang le litsela tse itšetlehileng ka PI3K. Sena se lumella bafuputsi ho batlisisa mesebetsi eo PI3K le litsela tse amanang le eona li e bapalang lits'ebetsong tse kang kholo ea sele, ho ata ha lisele, apoptosis, khoebo ea ka hare ho sele, le matla a lera.

Wortmannin e sebelisitsoe haholo lithutong ho utloisisa mekhoa ea limolek'hule ea mafu a fapaneng, ho kenyeletsoa kankere, ho ruruha, mafu a autoimmune le mafu a methapo ea kutlo. E ka thusa bafuputsi ho tseba lipheo tse ka bang teng tsa phekolo le ho nts'etsapele maano a macha a kalafo bakeng sa maemo ana.

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Tšebeliso le Phello

Ho utloisisa kankere: Matšoao a PI3K hangata a sitisoa liseleng tsa kankere, e leng se lebisang kholong e sa laoleheng ea lisele le ho phela. Wortmannin e sebelisitsoe ho ithuta karolo ea PI3K nts'etsopele ea kankere, tsoelo-peleng le ho hanyetsa phekolo.

Ho batlisisa ho ruruha: Letšoao la PI3K le lona le ameha taolong ea likarabo tsa 'mele oa ho itšireletsa mafung le ho ruruha. Wortmannin e sebelisitsoe ho hlahloba mekhoa e nepahetseng eo PI3K e kenyang letsoho ho ruruha ka eona le ho khetholla lipheo tse ka bang teng bakeng sa mekhoa ea ho thibela ho ruruha.

Ho ithuta ka autophagy: Autophagy ke ts'ebetso ea sele e kenyeletsang ho senyeha le ho sebelisoa hape ha likarolo tsa sele. Litsela tsa lipontšo tsa PI3K li bapala karolo ea bohlokoa ho laoleng autophagy. Wortmannin e sebelisitsoe ho batlisisa menehelo e itseng ea PI3K ho autophagy le ho sekaseka mekhoa ea eona ea limolek'hule.

Ho hlahloba mafu a ho senyeha ha methapo: Letšoao la PI3K le ameha mafung a 'maloa a ho senyeha ha methapo, joalo ka lefu la Alzheimer's le la Parkinson. Wortmannin e sebelisitsoe ho ithuta ho kenella ha PI3K ho pathogenesis ea mafu ana le ho khetholla lipheo tse ka bang teng tsa phekolo.

Ho paka Sehlahisoa:

Tlhahisoleseling e 'Ngoe:

Sebopeho	C23H24O8
Teko	99%
Ponahalo	Phofo e tšoeu
Nomoro ea CAS	19545-26-7
Ho paka	E nyane le e ngata
Bophelo ba Shelofo	lilemo tse 2
Polokelo	Boloka sebakeng se pholileng le se omileng
Setifikeiti	ISO.