Trimethylsulfoxonium iodide CAS:1774-47-6

Iodide ea Trimethylsulfoxonium e ka ba le lits'ebeliso tse fapaneng tlhahisong ea lintho tse phelang e le reagent e feto-fetohang le e mahareng bakeng sa liphetoho tse fapaneng. Motsoako ona o ka sebetsa e le moemeli oa methylating, o nolofalletsang ho kenngoa ha lihlopha tsa methyl ho limolek'hule tsa lintho tse phelang ka liketso tsa S-methylation. Ho feta moo, o ka nka karolo k'hemistring ea ylide, o thusa ho thehoa ha li-ylides bakeng sa liketso tsa mofuta oa Wittig tlhahisong ea li-olefin. Ho feta moo, iodide ea trimethylsulfoxonium e sebelisoa ho lokiseng li-ketone tsa α-halo le li-ketone tsa α-iodo, e leng li-intermediate tsa bohlokoa k'hemistring ea lintho tse phelang bakeng sa ts'ebetso e eketsehileng le phetoho ho limolek'hule tse rarahaneng. Phuputsong ea meriana, iodide ea trimethylsulfoxonium e ka fumana thuso tlhahisong ea metsoako e sebetsang ea bioactive, li-intermediate tsa meriana, le li-intermediate tsa lithethefatsi. Ka ho kenyelletsa reagent ena litseleng tsa maiketsetso, bafuputsi ba ka fihlella mefuta e mengata ea limolek'hule tse sebetsang tse nang le mesebetsi e ka bang teng ea meriana, e lumellang nts'etsopele ea meriana e mecha kapa li-agent tsa kalafo. Bokhoni ba motsoako oa ho fetola meaho ea limolek'hule le ho hlahisa lihlopha tse itseng tsa ts'ebetso bo kenya letsoho moralong le ntlafatsong ea li-intermediate tsa lithethefatsi tse nang le thepa e lakatsehang le litlamorao tsa baeloji. Ho feta moo, trimethylsulfoxonium iodide e ka sebetsa e le sesebelisoa sa bohlokoa lipatlisisong tsa lik'hemik'hale bakeng sa ho batlisisa mekhoa ea karabelo, ho hlahloba litsela tse ncha tsa maiketsetso, le ho ntlafatsa katleho ea liphetoho tsa lintho tse phelang. Ho sebetsa ha eona ka tsela e ikhethang le ho tenyetseha ho etsa hore e be sesebelisoa se thusang matsohong a litsebi tsa lik'hemik'hale tsa maiketsetso tse batlang ho fihlella limolek'hule tse rarahaneng tse nang le meaho le thepa e etselitsoeng tsona. Ho tsoela pele ho hlahloba ts'ebeliso ea trimethylsulfoxonium iodide masimong a fapaneng a k'hemistri le saense ea meriana ho ka lebisa ho litšibollo tse ncha, tsoelo-pele ea mokhoa oa maiketsetso, le ho kopanngoa ha metsoako e nang le melemo e ka bang teng ea phekolo.