N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide CAS:262368-30-9

N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide e sebetsa e le setsi se sebetsang ka ho fetisisa ho tsoakoeng ha lintho tse phelang le k'hemistri ea meriana. Litšobotsi tsa eona tse ikhethang tsa sebopeho li e etsa motheo oa bohlokoa bakeng sa ho lokisa metsoako e sebetsang ka baeloji, ho kenyeletsoa meriana le lik'hemik'hale tsa temo. Motsoako ona o ka fetoloa ka lik'hemik'hale ho hlahisa lihlopha tse itseng tse sebetsang kapa ho fetola thepa ea oona ea meriana, ho lumella nts'etsopele ea bakhethoa ba meriana ba bacha le lisebelisoa tsa lipatlisiso. Ho sibolloeng le nts'etsopele ea lithethefatsi, N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide e sebelisoa bakeng sa ho kopanya limolek'hule tse ka bang mafolofolo ka lits'ebetso tsa kalafo. Bafuputsi ba sebelisa reactivity ea eona ea lik'hemik'hale le likarolo tsa pharmacophore ho rala bakhethoa ba meriana ba bacha ba shebaneng le litsela tse fapaneng tsa mafu, joalo ka mafu a methapo ea kutlo, mofetše le mafu a tšoaetsanoang. Ka ho kenyelletsa motsoako ona ka har'a li-scaffolds tsa limolek'hule, bo-rasaense ba ka hlahloba likamano tsa sebopeho le ts'ebetso, ba ntlafatsa matla a lithethefatsi, 'me ba ntlafatsa khetho ho ea lipheong tse itseng tsa baeloji. Ho feta moo, N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide e bapala karolo ea bohlokoa lipatlisisong tsa k'hemistri ea meriana tse reretsoeng ho sibolla le ho ntlafatsa metsoako ea meriana ka liprofayili tse ntlafetseng tsa katleho le polokeho. Ts'ebeliso ea eona e atolohela ho nts'etsopele ea li-lead tse ka bang teng tsa lithethefatsi, li-enzyme inhibitors, li-receptor modulator, le li-probe tsa tlhahlobo bakeng sa lipatlisiso tsa bongaka. Ka lithuto tse hlophisitsoeng le liphetoho tsa limolek'hule tse kenyeletsang motsoako ona, bo-rasaense ba ka ntlafatsa kutloisiso ea likamano tsa lithethefatsi le sepheo, kananelo ea limolek'hule, le metabolism ea lithethefatsi, e leng se bulang tsela bakeng sa mekhoa e mecha ea phekolo le tsoelo-pele ea meriana.