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N,N-Bis(2-hydroxyethyl) -2-aminoethanesulfonic acid letsoai la sodium CAS:66992-27-6
N,N-Bis(2-hydroxyethyl) -2-aminoethanesulfonic acid letsoai la sodium, le tsejoang hape e le HEPES sodium letsoai, ke motsoako oa lik'hemik'hale o atisang ho sebelisoa e le pH buffering agent lilaboratoring tsa baeloji le lik'hemik'hale.E thusa ho boloka pH e tsitsitseng, e etsa hore e be e loketseng bakeng sa lits'ebetso tse kang setso sa lisele, liteko tsa li-enzyme, lithuto tsa protheine, electrophoresis, le metsoako ea meriana.HEPES letsoai la sodium le netefatsa maemo a nepahetseng bakeng sa lits'ebetso tsa baeloji le ho ntlafatsa ho nepahala le ho ts'epahala ha liphetho tsa liteko.
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2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM SALT CAS:76204-02-9
2′-(4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid letsoai la sodium ke motsoako oa lik'hemik'hale o atisang ho sebelisoa litekong tsa ho hlahloba le ho etsa lipatlisiso.Ke motsoako oa fluorescent o tsoang ho sialic acid, mofuta oa molek'hule ea carbohydrate e fumanehang holim'a lisele.
Motsoako ona o sebelisoa e le substrate bakeng sa li-enzyme tse bitsoang neuraminidases, tse sebetsang ho tlosa masala a sialic acid ho glycoprotein le glycolipids.Ha li-enzyme tsena li sebetsa ho 2′- (4-Methylumbelliferyl) -alpha-DN-acetylneuraminic acid letsoai la sodium, e ntša sehlahisoa sa fluorescent se tsejoang e le 4-methylumbelliferon.
Fluorescence e hlahisoang ke motsoako e ka lekanyetsoa le ho lekanyetsoa, ho fana ka tlhahisoleseding mabapi le mosebetsi oa li-enzyme tsa neuraminidase.Sena se bohlokoa haholo thutong ea mafu le maemo a fapaneng a amanang le metabolism ea sialic acid.
Motsoako ona o boetse o sebelisetsoa merero ea tlhahlobo, joalo ka ho lemoha mafu a vaerase a amang tšebetso ea neuraminidase.Litlhahlobong tsena, motsoako o sebelisetsoa ho khetholla boteng ba mefuta e itseng ea kokoana-hloko kapa ho lekola katleho ea li-neuraminidase inhibitors liphekong tsa antiviral.
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TAPSO CAS: 68399-81-5 Theko ea Moetsi
TAPSO (3-[N-tris(hydroxymethyl)methyl]amino] -2-hydroxypropanesulfonic acid) ke zwitterionic buffer e atisang ho sebelisoa lipatlisisong tsa baeloji le biochemical.Ke sesebelisoa se hloahloa se nang le pKa e haufi le pH ea 'mele, e etsang hore e tšoanelehe bakeng sa ho boloka pH e tsitsitseng litekong tsa baeloji.Hangata TAPSO e sebelisoa ho hloekisa liprotheine, litlhahlobo tsa enzyme, setso sa lisele, le lits'ebetso tsa electrophoresis.Ho qhibiliha ha eona ho phahameng ho metsi le ho kena-kenana le mekhoa ea likokoana-hloko ho etsa hore e be khetho e ratoang sechabeng sa saense.TAPSO e tsejoa ka phello e fokolang mosebetsing oa enzyme 'me hangata e sebelisoa e le mokhoa o mong oa lisebelisoa tse ling tse kang Tris kapa phosphate buffers.
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N-Acetyl-L-cysteine CAS: 616-91-1
N-Acetyl-L-cysteine (NAC) ke mofuta o fetotsoeng oa amino acid cysteine.E fana ka mohloli oa cysteine 'me e ka fetoloa habonolo ho tripeptide glutathione, antioxidant e matla 'meleng.NAC e tsebahala ka thepa ea eona ea antioxidant le mucolytic, e e etsang hore e be molemo lits'ebetsong tse fapaneng tsa bophelo bo botle.
E le antioxidant, NAC e thusa ho sireletsa lisele ho tsoa tšenyong e bakoang ke li-radicals tsa mahala, mefuta ea oksijene e sebetsang le chefo.E boetse e ts'ehetsa glutathione synthesis, e bapalang karolo ea bohlokoa lits'ebetsong tsa 'mele tsa detoxification le ho boloka sesole sa' mele se phetseng hantle.
NAC e ithutoe ka melemo ea eona e ka bang teng bophelong ba phefumoloho, haholo-holo ho batho ba nang le maemo a kang bronchitis e sa foleng, COPD le cystic fibrosis.E atisa ho sebelisoa e le expectorant ho thusa ho tšesaane le ho lokolla mucus, ho etsa hore ho be bonolo ho hloekisa litsela tsa moea.
Ho feta moo, NAC e bontšitse tšepiso ea ho tšehetsa bophelo bo botle ba sebete ka ho thusa ho tlosoa ha lintho tse chefo, tse kang acetaminophen, e tloaelehileng ea ho kokobetsa bohloko.E ka boela ea e-ba le liphello tse sireletsang khahlanong le tšenyo ea sebete e bakoang ke ho noa joala.
Ntle le thepa ea eona ea ts'ehetso ea antioxidant le phefumoloho, NAC e 'nile ea hlahlojoa bakeng sa melemo ea eona e ka bang teng bophelong ba kelello.Liphuputso tse ling li fana ka maikutlo a hore e ka ba le phello e ntle mathateng a maikutlo, joalo ka khatello ea maikutlo le khatello ea maikutlo (OCD).
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PIPES CAS: 5625-37-6 Theko ea Moetsi
PIPES (piperazine-1,4-bisethanesulfonic acid) ke motsoako oa zwitterionic buffering o atisang ho sebelisoa lipatlisisong tsa baeloji le lik'hemik'hale.Ke sekoaelo se sebetsang sa pH se nang le bokhoni bo phahameng ba ho boloka maemo a tsitsitseng a pH ho tloha ho 6.1 ho isa ho 7.5.PIPES e na le tšitiso e fokolang ho li-biomolecules 'me e loketse litlhahlobo tse itšetlehileng ka mocheso.Hangata e sebelisoa mekhoeng ea gel electrophoresis le tlhahiso ea meriana e le moemeli oa botsitso.Ka kakaretso, PIPES ke motsoako o feto-fetohang le o sebelisoang haholo maemong a fapaneng a liteko.
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2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniumM-9-carboxylate 4′-NHS Ester CAS:194357-64-7
2',6'-DiMethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4'-NHS ester ke motsoako oa lik'hemik'hale o nang le mohaho o rarahaneng oa limolek'hule.E na le sehlopha sa sulfopropylacridinium le sehlopha se sebetsang sa carboxylate ester.Ho ba teng ha karolo ea ester ho bontša hore e sebetsa 'me e ka sebelisoa e le moemeli oa ho ngola kapa oa ho fetola li-biomolecules.
Sehlopha sa sulfopropylacridinium sa kompone se fana ka maikutlo a hore e kanna ea ba le ts'ebeliso e ka bang teng litekong tse thehiloeng ho fluorescence, moo e ka sebelisoang e le mochini o hlahlobang oa fluorescent kapa dae bakeng sa ho bona le ho sekaseka li-biomolecules.E kanna ea ba le bohlokoa lithutong tsa lits'ebetso tsa cellular, joalo ka pontšo ea intracellular calcium.
Ho kenyelletsoa ha sehlopha sa ester sa NHS ho bontša hore e ka itšoara ka li-amine tse ka sehloohong, tse kang tse fumanoang liprotheine kapa li-peptide, ho etsa li-amide bond tse tsitsitseng.Reactivity ena e etsa hore e be molemo bakeng sa lits'ebetso tsa bioconjugation, moo e ka sebelisoang ho tšoaea kapa ho fetola limolek'hule tse ling tse sebetsang, joalo ka fluorophores kapa li-tag.
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5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide CAS:4264-82-8
5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide ke motsoako o sebelisoang lithutong tse fapaneng tsa biochemical, haholo-holo bakeng sa ho lemoha le ho bona tšebetso ea enzyme.Ke substrate e ka kenngoa ka hydrolyzed ka li-enzyme tse itseng, e leng se bakang ho lokolloa ha sehlahisoa se mebala kapa sa fluorescent.
Motsoako ona o sebelisoa hangata litekong tsa ho bona boteng le tšebetso ea li-enzyme tse kang beta-galactosidase le beta-glucuronidase.Li-enzyme tsena li qhekella lihlopha tsa acetyl le glucosaminide ho tloha substrate, e leng se lebisang ho thehoeng ha chromophore e putsoa kapa e tala.
Sebopeho se ikhethileng sa 5-Bromo-4-chloro-3-indolyl-N-acetyl-beta-D-glucosaminide se lumella ho lemoha habonolo le ho lekanya mosebetsi oa enzyme.Tšebeliso ea eona mekhoeng e fapaneng ea liteko, ho kenyelletsa histochemistry, immunohistochemistry, le litlhahlobo tse thehiloeng liseleng, e tlatselitse kutloisisong e ntle ea mesebetsi ea enzyme.
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Letsoai la letsoai la sodium CAS: 139-41-3 Theko ea Moetsi
N,N-Bis(2-hydroxyethyl) glycine sodium letsoai ke motsoako oa lik'hemik'hale o sebelisoang e le ntho e thibelang lits'ebetso tse fapaneng tsa biochemical le biophysical.E thusa ho boloka boemo ba pH bo tsitsitseng maemong a liteko, ho etsa hore e be molemo lithutong tsa enzyme, lipatlisiso tsa protheine, setso sa lisele, le mekhoa ea ho thibela Bophirimela.
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Spinosad CAS: 131929-60-7 Mofani oa Moetsi
Spinosad ke sehlopha sa 5 nicotinic acetylcholine receptor agonist, se bakang ho honyela ha mesifa le ho thothomela ho latelang ho ts'ebetso ea motor neuron.Ho pepeseha ha nako e telele ho baka ho holofala le lefu la matsetse.Lefu la letsetse le qala nakong ea metsotso e 30 kamora ho nooa, 'me ka mor'a lihora tse 4 ho felile.Spinosad ha e sebelisane le libaka tse tlamang tsa lintho tse ling tse bolaeang likokoanyana (GABA-ergic kapa nicotinic).
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Rotenone CAS: 83-79-4 Mofani oa Moetsi
Rotenone ke chefo ea mpa le ea ho kopana bakeng sa arthropods.Ketso ea eona e potlakileng ea ho kokota e hlahisoa ke ho fokotsa ho fumaneha ha nicotinamide adenine dinucleotide ho sebetsa e le cofactor litseleng tse fapaneng tsa biochemical ho kenyelletsa potoloho ea Krebs, ka hona e thibela li-enzyme tsa phefumoloho ea mitochondrial.
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Diazinon CAS: 333-41-5 Mofani oa Moetsi
Diazinon e fumaneha ka mokhoa oa mokelikeli o se nang 'mala kapa o lefifi.E qhibiliha hanyenyane metsing empa e qhibiliha haholo ka petroleum ether, joala le benzene.Diazinon e sebediswa bakeng sa taolo ya mefuta e fapaneng ya temo le disenyi tsa malapa.Tsena li kenyelletsa tse senyang lijalo mobung, limela tsa mekhabiso, litholoana, meroho le lijalo le tse senyang lijalo ka tlung tse kang lintsintsi, matsetse le maphele.
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Avermectin CAS: 71751-41-2 Mofani oa Moetsi
Abamectin (Avermectin) ke chefo ea methapo ea kutlo.Mochine oa eona o lebisitse ho GABAA receptor ea likokoanyana tsa neuron synapse kapa neuromuscular synapse, e sitisang phetiso ea tlhahisoleseling ea methapo ea kutlo, e leng ho susumetsa methapo ea kutlo ho lokolla neurotransmitter inhibitor γ-aminobutyric acid (GA-BA), e leng se lebisang ho buloa ho hoholo ha methapo ea kutlo. Mocha oa GABA-gated chloride o nang le phello ea chloride-activating.
