N-Acetyl-D-proline CAS:59785-68-1

N-Acetyl-D-proline e na le bohlokoa bo boholo k'hemistring ea peptide e le karolo ea bohlokoa bakeng sa ho kopanngoa ha li-peptide le li-peptidomimetics. Jwalo ka derivative ea D-proline e nang le acetyl, e sebetsa e le mokhoa o feto-fetohang bakeng sa ho kenya masala a itseng a chiral ka har'a liketane tsa peptide ka mekhoa ea ho kopanya peptide ea mohato o tiileng le mohato oa tharollo. Bafuputsi le litsebi tsa lik'hemistri ba sebelisa N-Acetyl-D-proline ho iketsetsa tatellano ea li-peptide ka taolo e nepahetseng ea stereochemical, e nolofalletsang moralo oa metsoako e mecha ea bioactive le li-peptide tsa kalafo tse shebaneng le li-receptor, li-enzyme, kapa li-transporter litsamaisong tsa baeloji. Ho feta moo, N-Acetyl-D-proline e sebelisoa e le motheo oa chiral tlhahisong ea metsoako ea meriana, moo stereochemistry ea eona e ikhethang e leng ea bohlokoa bakeng sa ho kopanngoa ha meriana ea chiral le metsoako ea bioactive. Chirality ea eona le botsitso li etsa hore e be ea bohlokoa tlhahisong ea lihlahisoa tsa meriana, e ntlafatsa thepa ea meriana le ts'ebetso ea baeloji ea bakhethoa ba ho qetela ba lithethefatsi. Ho feta moo, N-Acetyl-D-proline e sebelisoa lipatlisisong tsa biochemical ho ithuta metabolism ea proline, ts'ebetso ea protheine le kinetics ea enzyme. Karolo ea eona ho hlakiseng litsela tsa sele le lits'ebetso tsa metabolism e thusa ho utloisisa mesebetsi ea proline lits'ebetsong tsa baeloji le litlamorao tsa eona tse ka bang teng bophelong bo botle le mafung. Ka bokhutšoanyane, N-Acetyl-D-proline e bapala karolo ea bohlokoa ho ntšetseng pele lipatlisiso tsa mahlale, nts'etsopele ea meriana le lithuto tsa biochemical, e fa bo-rasaense le litsebi sesebelisoa se feto-fetohang sa ho hlahloba lits'ebetso tse fapaneng tsa li-derivatives tsa proline ho sibolloeng ha lithethefatsi, ho hlophisoa ha peptide le lipatlisiso tsa biochemical.