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Mirabegron CAS:223673-61-8 Manufacturer Supplier Setšoantšo se hlahang
  • Mirabegron CAS: 223673-61-8 Mofani oa Moetsi

Mirabegron CAS: 223673-61-8 Mofani oa Moetsi

Mirabegron ke bakeng sa phekolo ea ho potlaka, maqhubu a ho ntša metsi, le ho hloka ts'oaetso ea ho ntša metsi ho amanang le senya se feteletseng (OAB).Mirabegron e entsoe ka ho kopanya 4-nitrophenethyl amine ho (R) -2-hydroxy-2-phenylacetic acid.Amide e hlahisoang e fokotsoa ho amine.Sehlopha sa nitro se fokotsehile mme sephetho se kopantsoe le 2-(2-aminothiazol-4-yl) acetic acid ho fana ka mirabegron.


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Mirabegron ke agonist e sebetsang ka molomo ea β3-adrenoceptor hajoale e ntse e ntlafatsoa ke Astellas Pharma bakeng sa kalafo ea senya se sengata (OAB).Lithethefatsi ke mohanyetsi oa nanomolar EC50 khahlanong le liteko tsa batho tsa β3-AR tsa biochemical tse nang le khetho e ntle ho feta b1- le β2-ARs.Mirabegron e bonts'a mokhoa o mocha ka ho lebisa tlhokomelo ho β3-AR bakeng sa ho phomola ha senya ho thusa ho laola matšoao a OAB a kang ho eketseha ha ho potlaka ha moroto le makhetlo a mangata le ho potlaka ho sa khonehe.Leha ho le joalo, mirabegron ke cytochrome P450 2D6 inhibitor, 'me e hlahisa ngongoreho ea tšebelisano ea lithethefatsi le lithethefatsi le tsamaiso e tšoanang ea li-substrates tse ling tsa cytochrome P450 2D6.

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Tlhahisoleseling e 'Ngoe:

Sebopeho Setšoantšo sa C21H24N4O2S
Tlhahlobo 99%
Ponahalo Phofo e tšoeu ho isa ho e 'mala o mosehla
Nomoro ea CAS. 223673-61-8
Ho paka 25KG
Shelf Life lilemo tse 2
Polokelo Boloka sebakeng se phodileng le se omileng
Setifikeiti ISO.
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