Mirabegron CAS:223673-61-8 Mofani oa Moetsi

Mirabegron ke bakeng sa kalafo ea ho potlaka, khafetsa ea moroto, le ho se khone ho itšoarella ha moroto ho amanang le senya se sebetsang ka ho feteletseng (OAB). Mirabegron e hlahisoa ka ho kopanya 4-nitrophenethyl amine le (R)-2-hydroxy-2-phenylacetic acid. Amide e hlahisoang e fokotsoa ho ba amine. Sehlopha sa nitro sea fokotsoa 'me se hlahang se kopanngoa le 2-(2-aminothiazol-4-yl) acetic acid ho fana ka mirabegron.

Odara kapa Kopa Khoteshene

Qaqiso ea Sehlahisoa

Li-tag tsa Sehlahisoa

Tšebeliso le Phello

Mirabegron ke agonist e sebetsang ka molomo e sebetsang ka β3-adrenoceptor e ntseng e ntshetswa pele ke Astellas Pharma bakeng sa kalafo ya senya se sebetsang ka ho feteletseng (OAB). Moriana ona ke mohanyetsi wa nanomolar EC50 kgahlanong le diteko tsa biochemical tsa β3-AR tsa batho ka kgetho e ntle hodima b1- le β2-ARs. Mirabegron e bontsha mokgwa o motjha ka ho shebana le β3-AR bakeng sa ho phomotsa senya ho thusa ho laola matshwao a OAB a kang ho potlaka ho eketsehileng ha moroto le kgafetsa le ho se kgone ho itshwara ka potlako. Leha ho le jwalo, mirabegron ke mothibi wa cytochrome P450 2D6, mme e phahamisa ngongoreho mabapi le tshebedisano ya dithethefatsi le dithethefatsi le tsamaiso e nngwe ya di-substrate tse ding tsa cytochrome P450 2D6.

Sampole ea Sehlahisoa

Ho paka Sehlahisoa:

Tlhahisoleseling e 'Ngoe:

Sebopeho	C21H24N4O2S
Teko	99%
Ponahalo	Phofo e tšoeu ho isa ho e mosehla o moputsoa
Nomoro ea CAS	223673-61-8
Ho paka	25KG
Bophelo ba Shelofo	lilemo tse 2
Polokelo	Boloka sebakeng se pholileng le se omileng
Setifikeiti	ISO.