methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate CAS:362703-30-8

Methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate e bapala karolo ea bohlokoa e le mokena-lipakeng o feto-fetohang ho kopanyeng metsoako e rarahaneng, e sebetsang ka lintho tse phelang e nang le lits'ebetso tse ka bang teng tsa meriana. Ho kenyelletsoa ha eona meralong ea limolek'hule ho lumella bafuputsi ho hlahloba bakhethoa ba meriana ba bacha ba shebaneng le libaka tsa kalafo tse kang mafu a pelo le methapo ea mali, mathata a tsamaiso ea methapo ea bohareng, kapa li-antiviral. Boteng ba khubu ea tetrahydropyran le ts'ebetso ea cyano li hlahisa reactivity e itseng le thepa ea pharmacophoric, e leng se etsang hore e be ea bohlokoa bakeng sa lipatlisiso tsa k'hemistri ea meriana. Maitekong a ho sibolla lithethefatsi, motsoako ona o ka sebetsa e le sebaka sa ho qala ho rala bakhethoa ba meriana ba ka bang teng, o sebelisa likarolo tsa ona tsa sebopeho ho fetola ts'ebetso ea baeloji le thepa ea pharmacokinetic. Ho feta moo, sehlopha sa cyano se ka sebetsa e le mokena-lipakeng o feto-fetohang bakeng sa ho ntšoa ho eketsehileng, ho lumella ho hlahloba likamano tsa sebopeho le ts'ebetso le nts'etsopele ea bakhethoa ba meriana ba bacha. Ho feta moo, libakeng tsa thuto le tsa indasteri, bafuputsi ba ka sebelisa motheo ona oa kaho ho lokisa lilaebrari tsa li-derivatives tse fapaneng bakeng sa lithuto tsa kamano ea sebopeho le ts'ebetso, ho nolofalletsa ho tsebahatsa metsoako ea loto e nang le litlamorao tse lakatsehang tsa baeloji. Karolo ea eona ho kopanyeng lik'hemik'hale e atoloha ho tlhahiso ea bakhethoa-lipakeng ba meriana le nts'etsopele ea mekhoa e mecha ea maiketsetso, e bonts'a thuso ea eona e pharaletseng mafapheng a saense. Ka kakaretso, Methyl 4-cyanotetrahydro-2H-pyran-4-carboxylate e bapala karolo ea bohlokoa ho phehelleng ho sibolloa ha meriana e mecha le lipatlisiso tsa lik'hemik'hale, e fana ka sethala sa nts'etsopele ea limolek'hule tse fapaneng tse sebetsang ka baeloji le metsoako e mahareng ea meriana.