TRIMETHYLSULFOXONIUM CHLORIDE CAS:5034-06-0

Trimethylsulfoxonium chloride e sebetsa e le reagent e feto-fetohang ho tsoakoeng ha lintho tse phelang, haholo-holo karabelong ea oxidation ea Swern bakeng sa ho fetola li-alcohol hore e be aldehydes kapa ketones. Motsoako ona o sebetsa e le karolo ea bohlokoa mokhoeng oa oxidation oa Swern, hammoho le oxalyl chloride le dimethylsulfoxide, e nolofalletsang oxidation e sebetsang hantle le e khethileng ea li-alcohol tsa mantlha le tsa bobeli ho ba aldehydes le ketones. Tšebeliso ea trimethylsulfoxonium chloride ts'ebetsong ea oxidation ea Swern e fana ka melemo e kang maemo a bobebe a karabelo, chai e ngata, le ho lumellana le lihlopha tse fapaneng tse sebetsang, e leng se etsang hore e be sesebelisoa sa bohlokoa ho tsoakoeng ha limolek'hule tse rarahaneng tsa lintho tse phelang. Ho feta moo, trimethylsulfoxonium chloride e sebelisoa e le moemeli oa methylating k'hemistri ea lintho tse phelang, e lumellang methylation ea li-nucleophile tse fapaneng tlas'a maemo a bobebe. Reagent ena e ka nolofatsa ho kenngoa ha lihlopha tsa methyl ka metsoako ea lintho tse phelang, e nolofalletsang ho kopanngoa ha lihlahisoa tse fapaneng tsa methylated tse nang le meaho le thepa e etselitsoeng motho ka mong. Ho feta moo, trimethylsulfoxonium chloride e sebediswa ho lokiseng α-chloroketones le α-bromoketones, di-intermediate tsa bohlokwa ho organic synthesis bakeng sa diphetoho tse ding le ho nkuwa ha tsona. Ho fumanweng ha k'hemistri ya meriana le dithethefatsi, trimethylsulfoxonium chloride e ka sebediswa ho qaptjweng ha di-intermediate tsa meriana le dikokwana-hloko tse sebetsang. Ka ho kenyelletsa reagent ena ditseleng tsa maiketsetso, bafuputsi ba ka fihlella mefuta e fapaneng ya dikokwana-hloko tse nang le mesebetsi e ka bang teng ya dikhemistri, e leng se nolofalletsang ho batlisisa bakgetho ba batjha ba dithethefatsi le ntshetsopele ya meriana e metjha. Bokgoni ba motsoako wa ho fetola dibopeho tsa dimolek'hule le ho thusa dikarabelo tsa bohlokwa tsa organic bo thusa ho rala le ho ntlafatsa dimolek'hule tse nang le ditlamorao tse lakatsehang tsa baeloji le thepa ya kalafo. Ka kakaretso, trimethylsulfoxonium chloride e bapala karolo ya bohlokwa ho organic synthesis, e fa dikhemistri tsa maiketsetso sesebediswa sa bohlokwa bakeng sa diphetoho tse kang oxidation, methylation, le tsamaiso ya sehlopha se sebetsang. Ho tenyetseha ha yona, maemo a yona a bobebe a karabelo, le ho tsamaellana le di-substrate tse fapaneng ho e etsa reagent ya bohlokwa lebokoseng la disebediswa tsa dikhemistri tsa organic le bafuputsi ba sebetsang ho fumanweng ha dithethefatsi, k'hemistri ya meriana le chemical synthesis.