Boc-Phe-ONp CAS:7536-56-0

Boc-Phe-ONp e bapala karolo ea bohlokoa tlhahisong ea peptide, haholo-holo tlhahisong ea peptide ea mohato oa tharollo le tlhahisong ea peptide ea mohato o tiileng (SPPS). Jwalo ka derivative e sirelelitsoeng ea amino acid, e sebetsa e le motheo oa bohlokoa oa ho kenyelletsa masala a phenylalanine ka tatellano ea peptide. Ho SPPS, Boc-Phe-ONp e sebelisoa ho kenyelletsa likarolo tsa phenylalanine ka mokhoa o ikhethileng nakong ea kopano ea liketane tsa peptide ka mohato holim'a litšehetso tse tiileng, ha tlhahisong ea mohato oa tharollo, e nolofalletsa ho thehoa ha litlamo tsa peptide liketsong tse thehiloeng tharollong. Bafuputsi le bo-rasaense ba meriana ba sebelisa Boc-Phe-ONp ho theha li-peptide tse etselitsoeng ka tatellano e itseng ea amino acid e ntlafalitsoeng bakeng sa liteko tsa baeloji, lithuto tsa sebopeho le nts'etsopele ea lithethefatsi. Ka ho sebelisa reactivity ea sehlopha sa 4-nitrophenyl ester, ba ka fihlella ho hokahana ka katleho le lihlopha tsa amino, e leng se lebisang ho atolosoeng ho laoloang ha liketane tsa peptide le tlhahiso ea meaho e fapaneng ea peptide. Ho tenyetseha ha Boc-Phe-ONp ho e etsa sesebelisoa sa bohlokoa masimong a fapaneng joalo ka biochemistry, pharmacology le biotechnology. Ho tsamaellana ha eona le melaoana e tloaelehileng ea ho kopanya li-peptide, chai e ngata, le ts'ebetso e tšepahalang li tlatsetsa ts'ebelisong ea eona e pharaletseng libakeng tsa thuto le tsa indasteri. Ebang e sebelisoa lipatlisisong tsa motheo kapa boitekong ba ho sibolla lithethefatsi, Boc-Phe-ONp e thusa ho theha li-peptide tse tšehetsang tsoelo-pele ea bohlokoa saenseng ea bongaka le boqapi ba kalafo.