Boc-D-Phe-ONp CAS:16195-70-9

Boc-D-Phe-ONp e bapala karolo ea bohlokoa tlhahisong ea peptide, haholo-holo tlhahisong ea peptide ea mohato o tiileng (SPPS) le tlhahisong ea peptide ea mohato oa tharollo. Jwalo ka derivative e sirelelitsoeng ea amino acid, e nolofalletsa ho kenngoa ha masala a D-phenylalanine ka tatellano ea peptide. Ho SPPS, Boc-D-Phe-ONp e sebelisoa ho kenyelletsa ka mokhoa o ikhethileng li-unit tsa D-phenylalanine nakong ea kopano ea liketane tsa peptide ka mohato holim'a litšehetso tse tiileng, ha tlhahisong ea mohato oa tharollo, e nolofalletsa ho thehoa ha libonto tsa peptide liketsong tse thehiloeng tharollong. Bafuputsi le bo-rasaense ba meriana ba sebelisa Boc-D-Phe-ONp ho theha li-peptide tse etselitsoeng ka tatellano e itseng ea D-amino acid e ntlafalitsoeng bakeng sa liteko tsa baeloji, lithuto tsa sebopeho le nts'etsopele ea lithethefatsi. Ha ba sebelisa reactivity ea sehlopha sa 4-nitrophenyl ester, ba ka fihlella ho kopana ka katleho le lihlopha tsa amino, e leng se lebisang ho atolosoeng ho laoloang ha liketane tsa peptide le tlhahiso ea meaho e fapaneng ea peptide. Ho tenyetseha ha Boc-D-Phe-ONp ho e etsa sesebelisoa sa bohlokoa haholo masimong a fapaneng a kang biochemistry, pharmacology, le biotechnology. Ho lumellana ha eona le mekhoa e tloaelehileng ea ho kopanya peptide, chai e ngata, le ts'ebetso e tšepahalang ho tlatsetsa ts'ebelisong ea eona e pharaletseng libakeng tsa thuto le tsa indasteri. Ebang e sebelisoa lipatlisisong tsa motheo kapa boitekong ba ho sibolla lithethefatsi, Boc-D-Phe-ONp e thusa ho thehoa ha li-peptide tse tšehetsang tsoelo-pele ea bohlokoa saenseng ea bongaka le boqapi ba kalafo.