benzoylglycine CAS:495-69-2

Sebopeho se feto-fetohang sa benzoylglycine se nolofalletsa ts'ebeliso ea eona masimong a fapaneng, ho kenyeletsoa tlhahiso ea lintho tse phelang, k'hemistri ea meriana le lipatlisiso tsa biochemical, ho bonts'a bohlokoa ba eona e le motheo oa motheo oa kaho le tlhahlobo ea limolek'hule lipatlisisong tsa mahlale le lits'ebetsong tsa indasteri. Ka har'a tlhahiso ea lintho tse phelang le k'hemistri ea meriana, benzoylglycine e sebetsa e le selelekela sa bohlokoa bakeng sa ho lokisa metsoako ea meriana, metsoako ea heterocyclic, le limolek'hule tse sebetsang. Ho arabela ha eona ho lumella ho hlahisoa ha lihlopha tse sebetsang le liphetoho tsa sebopeho, ho nolofalletsa ho kopanngoa ha metsoako e fapaneng e nang le thepa e ka bang teng ea kalafo. Ho feta moo, ho kenella ha benzoylglycine ho kopanyeng le ho ntšoa ha peptide ho kenya letsoho nts'etsopele ea meriana e mecha e thehiloeng ho peptide, peptidomimetics, le li-probe tsa limolek'hule tse sebelisoang ho sibolloeng ha lithethefatsi le lipatlisisong tsa bongaka, ho totobatsa bohlokoa ba eona ho ntšetseng pele saense ea meriana le boqapi ba kalafo. Ho feta moo, benzoylglycine e fumana thuso lithutong tsa biochemical le metabolism e le tekanyetso ea biomarker le tlhahlobo bakeng sa ho batlisisa metabolism ea amino acid, litsela tsa ho senyeha ha protheine, le liketso tsa enzymatic. Karolo ea eona e le motsoako oa mohlala bakeng sa ho etsisa ho kopanngoa ha amino acid, acylation, le liketso tsa cleavage e fana ka temohisiso lits'ebetsong tsa 'mele, mekhoa ea mafu, le metabolism ea lithethefatsi, e tšehetsang ho hlakisoa ha litsela tsa biochemical le tlhaloso ea mathata a metabolism. Ho phaella moo, ts'ebeliso ea benzoylglycine e le sesebelisoa sa lipatlisiso ho mass spectrometry le chromatography e nolofalletsa ho lekanya le ho khetholla metabolites lisampoleng tsa baeloji, e tlatsetsa kutloisisong ea liprofaele tsa metabolism le li-biomarker tsa mafu, ka hona e thusa boiteko ba tlhahlobo le lipatlisiso masimong a biochemistry ea kliniki le meriana e ikhethileng. Ho feta moo, ts'ebeliso ea benzoylglycine e atolohela ho baeloji ea lik'hemik'hale le k'hemistri ea bioconjugation, moo e sebetsang e le sethala sa ho rala metsoako ea bioactive, li-probe tsa fluorescent, le li-agent tsa ho nka litšoantšo tsa limolek'hule. Ho kopanngoa ha eona le lihlopha tse shebaneng, li-fluorophore, kapa li-pharmacophore ho nolofalletsa kaho ea metsoako e etselitsoeng ho ithuta lits'ebetso tsa baeloji, ho bona likarolo tsa sele, le ho fetola mesebetsi ea baeloji, ho fana ka lisebelisoa tsa bohlokoa bakeng sa ho hlakisa liketsahalo tse rarahaneng tsa baeloji le ho nts'etsapele maano a macha bakeng sa ho hlahloba le kalafo ea mafu. Ho phaella moo, benzoylglycine e sebediswa dipatlisisong tsa thuto le tsa indasteri bakeng sa ho batlisisa mekgwa ya karabelo, ho ntshetsa pele ditsela tse ntjha tsa maiketsetso, le ho hlahloba mekgwa e metjha ya dikhemikhale. Ho tenyetseha ha yona le tshebediso ya yona ya maiketsetso di totobatsa bohlokwa ba yona ho ntshetseng pele tsebo ya saense, ho atolosa meedi ya k'hemistri ya tlhaho, le ho sebetsana le ditlhoko tse ntseng di fetoha tsa diindasteri tse fapaneng. Ka kakaretso, tshebediso e fapaneng ya benzoylglycine e totobatsa bohlokwa ba yona e le motswako o tenyetsehang o nang le ditshebediso tse pharaletseng tlhahisong ya tlhaho, k'hemistri ya meriana le dipatlisiso tsa biochemical, e totobatsa karolo ya yona e le karolo ya bohlokwa ho kganneng boqapi ba saense, dipatlisiso tsa dikhemikhale le kgatelopele ya bongaka.