4-Nitrophenyl Beta-D-glucuronide CAS: 10344-94-2

4-Nitrophenyl Beta-D-glucuronide ke motsoako oa lik'hemik'hale o entsoeng ka ho hokela molek'hule ea glucose ho sehlopha sa 4-nitrophenyl ka khokahano ea glycosidic. E sebelisoa hangata e le substrate litekong tsa enzymatic ho lemoha boteng le ts'ebetso ea β-glucuronidase, e leng enzyme e amehang metabolism ea lithethefatsi tse fapaneng le xenobiotics ho liphoofolo tse anyesang. Ha β-glucuronidase e le teng, e arola tlamo ea glycosidic pakeng tsa glucose le sehlopha sa 4-nitrophenyl, e leng se fellang ka ho lokolloa ha 4-nitrophenol, e ka fumanoang ka spectrophotometrically ho 400-420 nm. Karabelo ena ea enzymatic e fana ka tekanyo ea bongata ba ts'ebetso ea β-glucuronidase 'me hangata e sebelisoa e le sesebelisoa ho sibolloeng ha lithethefatsi, lithuto tsa chefo, le tlhahlobo ea kliniki.

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Ho lemoha mosebetsi oa β-glucuronidase: 4-NPBG e sebelisoa hangata e le substrate ea chromogenic ho lekola boteng le ts'ebetso ea β-glucuronidase lisampoleng tse fapaneng tsa baeloji. Enzyme e khaola tlamo ea glycosidic ea 4-NPBG, e hlahisa 4-nitrophenol, e ka lekanngoang ho sebelisoa spectrophotometry.

Lithuto tsa metabolism ea lithethefatsi: Kaha β-glucuronidase e bapala karolo ea bohlokoa metabolism ea lithethefatsi le xenobiotics, 4-NPBG e ka sebelisoa ho lekola ts'ebetso ea enzyme ena lithutong tsa metabolism ea lithethefatsi. E thusa ho utloisisa boholo le kinetics ea liketso tsa glucuronidation, tse bohlokoa bakeng sa ho tlosoa ha lithethefatsi le ho fumaneha ha tsona 'meleng.

Lithuto tsa Chefo: Metswako e meng ea chefo e ka fetoloa 'me ea ntšoa ka mokhoa oa li-conjugates tsa glucuronide. Ka ho sebelisa 4-NPBG e le substrate, bafuputsi ba ka hlahloba ts'ebetso ea β-glucuronidase liseleng tse fapaneng kapa mela ea sele ho lekola chefo e ka bang teng kapa litlamorao tse mpe tsa metsoako.

Tlhahlobo ea bongaka: Tekanyo ea ts'ebetso ea β-glucuronidase ho sebelisoa 4-NPBG e ka sebelisoa maemong a bongaka ho fumana mafu kapa maemo a itseng. Maemo a sa tloaelehang kapa ts'ebetso ea β-glucuronidase e ka bontša mathata a itseng a liphatsa tsa lefutso, ho se sebetse hantle ha sebete, kapa mofetše.

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Tlhahisoleseling e 'Ngoe:

Sebopeho	C12H13NO9
Teko	99%
Ponahalo	Phofo e tšoeu
Nomoro ea CAS	10344-94-2
Ho paka	E nyane le e ngata
Bophelo ba Shelofo	lilemo tse 2
Polokelo	Boloka sebakeng se pholileng le se omileng
Setifikeiti	ISO.