1,7-Dimethylindolin-2-e 'ngoe CAS: 67358-21-8

1,7-Dimethylindolin-2-one e bapala karolo ea bohlokoa e le mokena-lipakeng oa metsoako e rarahaneng, e sebetsang ka lintho tse phelang e nang le lits'ebetso tse ka bang teng tsa meriana. Ho kenyelletsoa ha eona meralong ea limolek'hule ho nolofalletsa bafuputsi ho hlahloba bakhethoa ba bacha ba meriana ba shebaneng le libaka tsa kalafo tse kang mathata a tsamaiso ea methapo ea methapo, li-antimicrobial agents, kapa lits'ebetso tsa k'hemistri ea thepa. Boteng ba indolinone core bo hlahisa reactivity e itseng le thepa ea pharmacophoric, e leng se etsang hore e be ea bohlokoa bakeng sa lipatlisiso tsa k'hemistri ea meriana. Maitekong a ho sibolla lithethefatsi, motsoako ona o ka sebetsa e le sebaka sa ho qala ho rala bakhethoa ba ka bang teng ba lithethefatsi, o sebelisa likarolo tsa oona tsa sebopeho ho fetola ts'ebetso ea baeloji le thepa ea pharmacokinetic. Ho feta moo, sebopeho se ikhethang sa molek'hule se fana ka menyetla ea ho fapanyetsana, e leng se ka lebisang nts'etsopele ea limolek'hule tse ncha tse nang le thepa e ntlafalitsoeng ea baeloji le liprofaele tse ntlafalitsoeng tsa pharmacokinetic. Ho feta moo, libakeng tsa thuto le tsa indasteri, bafuputsi ba ka sebelisa motheo ona ho lokisa lilaebrari tsa lintho tse fapaneng tse tsoang ho tsona bakeng sa lithuto tsa kamano ea sebopeho le mosebetsi, ho nolofalletsa ho tsebahatsa metsoako ea loto e nang le litlamorao tse lakatsehang tsa baeloji. Karolo ea eona ho kopanyeng lik'hemik'hale e atolohela tlhahisong ea li-intermediate tsa meriana le nts'etsopele ea mekhoa e mecha ea maiketsetso, e bonts'a thuso ea eona e pharaletseng mafapheng a saense. Ka kakaretso, 1,7-Dimethylindolin-2-one e bapala karolo ea bohlokoa ho phehelleng ho sibolloa ha lithethefatsi tse ncha le lipatlisiso tsa lik'hemik'hale, e fana ka sethala sa nts'etsopele ea limolek'hule tse fapaneng tse sebetsang ka baeloji le metsoako ea meriana.