trichloroaceticanhydride CAS:4124-31-6

Trichloroacetic anhydride (TCAA) e sebelisoa haholo lits'ebetsong tse fapaneng tšimong ea tlhahiso ea lintho tse phelang. Jwalo ka acylation reagent, TCAA e arabela ka katleho ka mefuta e mengata ea li-nucleophile, ho kenyeletsoa le alcohols, amines le thiols, ho theha li-acylated derivatives. Reactivation ena e etsa hore TCAA e be sesebelisoa sa bohlokoa bakeng sa phetoho le ts'ebetso ea metsoako ea lintho tse phelang libakeng tsa laboratori le tsa indasteri. Indastering ea meriana, TCAA e sebelisoa ho etseng metsoako ea meriana le metsoako e sebetsang ea meriana (APIs). Thepa ea eona ea acylating e nolofalletsa phetoho e khethiloeng ea lihlopha tse itseng tse sebetsang ka har'a limolek'hule tse rarahaneng, e tlatsetsang nts'etsopele ea metsoako e mecha ea meriana e nang le mesebetsi e ntlafalitsoeng ea baeloji. Ho feta moo, TCAA e fumana ts'ebeliso tlhahisong ea lik'hemik'hale tsa temo, moo e sebetsang e le motheo oa bohlokoa bakeng sa tlhahiso ea meriana e bolaeang limela, chefo e bolaeang likokoanyana le balaoli ba kholo ea limela. Ka ho nolofalletsa ho kenngoa ha lihlopha tsa acyl ho limolek'hule tse reriloeng, TCAA e nolofalletsa moralo le ho thehoa ha lihlahisoa tse tsoetseng pele tsa agrochemical ka katleho e ntlafetseng le tšusumetso e fokotsehileng ea tikoloho. Ntle le karolo ea eona merianang le lik'hemik'hale tsa temo, TCAA e sebelisoa ho kopanyeng lik'hemik'hale tse ikhethang le lik'hemik'hale tse ntle. Tšebeliso ea eona e atolohela ho fetoleng lihlahisoa tsa tlhaho, ho lokisa thepa bakeng sa lipatlisiso tsa lik'hemik'hale, le ho theha metsoako e tsoetseng pele e sebetsang bakeng sa lits'ebetso tse fapaneng tsa indasteri. Ka kakaretso, trichloroacetic anhydride (TCAA) e eme e le reagent e feto-fetohang le e ke keng ea lekanngoa tlhahisong ea lintho tse phelang, e bapala karolo ea bohlokoa phetohong, ho fapanyetsaneng, le ho theheng lik'hemik'hale tsa bohlokoa makaleng a mangata, ho kenyeletsoa meriana, lik'hemik'hale tsa temo le lik'hemik'hale tse ntle. Bokhoni ba eona ba ho kopanya li-nucleophile tse fapaneng ka mokhoa o ikhethileng bo totobatsa bohlokoa ba eona e le motheo oa ho haha ​​​​tharollo ea lik'hemik'hale tse ncha bakeng sa liphephetso le menyetla ea mehleng ena.