TOPS CAS:40567-80-4 Theko ea Moetsi

Sodium 3-(N-ethyl-3-methylanilino) propanesulfonate, eo hape e tsejoang e le MESNa, e na le phello e khethehileng le ts'ebeliso ho biochemistry le biology ea molek'hule.Haholo-holo e sebelisoa e le ntho e fokotsang bakeng sa tšireletso ea lihlopha tsa thiol (-SH) ka liprotheine le li-peptide.

MESNa e sebetsa e le moemeli ea matla oa ho fokotsa, ea khonang ho fetola li-bond tsa disulfide (-SS-) liprotheine ka lihlopha tsa sulfhydryl (-SH).Ts'ebetso ena ea phokotso e bohlokoa lits'ebetsong tse fapaneng tsa mahlale, ho kenyelletsa tlhahlobo ea protheine, tlhoekiso, le boenjiniere ba protheine.

Lisebelisoa tse ling tse ikhethileng tsa MESNa li kenyelletsa:

Protein Denaturation: MESNa e ka sebelisoa ho nyenyefatsa liprotheine ka ho roba litlamo tsa disulfide, ka hona ho senola sebopeho sa protheine le ho thusa tlhahlobo e tsoelang pele kapa tlhoekiso ea protheine.

Ho fokotsa Protein Aggregation: MESNa e ka thibela ho bokellana ha protheine ka ho fokotsa litlamo tsa disulfide, ho netefatsa botsitso ba protheine le ho qhibiliha ka tharollo.

Protein Labeling: MESNa e ka sebelisoa ho hlahisa lileibole kapa liphetoho ho masala a itseng a cysteine ​​​​ka liprotheine ka ho roba li-bond tsa disulfide le ho pepesa lihlopha tsa sulfhydryl (-SH).

Protein Refolding: MESNa e sebelisetsoa ho thusa protheine e pheta-pheta ka mor'a denaturation ka ho fokotsa litlamo tsa disulfide le ho thusa sebopeho se nepahetseng sa liprotheine.