CAS ea tert-Butylsulfinamide: 146374-27-8

tert-Butylsulfinamide, e tsejoang hape e le N-tert-butanesulfinamide kapa TBSA, ke reagent e feto-fetohang e sebelisoang haholo lits'ebetsong tse fapaneng tsa tlhahiso ea lintho tse phelang. Tšebeliso ea eona ea mantlha e ho kopanngoa ha asymmetric, moo e sebetsang e le thuso ea chiral ho susumetsa stereocontrol liketsong tse fapaneng tsa lik'hemik'hale. Ka ho sebelisa thepa e ikhethang ea steric le ea elektroniki ea tert-Butylsulfinamide, litsebi tsa lik'hemik'hale li ka fihlela maemo a holimo a enantioselectivity, li nolofatsa tlhahiso ea metsoako e hloekileng ea optically ea bohlokoa ho meriana, lik'hemik'hale tsa temo le lik'hemik'hale tse ntle. E 'ngoe ea tšebeliso ea bohlokoa ea tert-Butylsulfinamide ke ho eketsa enantioselective ea li-reagent tsa organometallic ho imines, e nolofalletsang kaho ea li-amine tsa chiral, tse atileng limolek'huleng tse sebetsang ka baeloji. Ho feta moo, tert-Butylsulfinamide e fumane ts'ebeliso liketsong tsa phokotso ea asymmetric, e fanang ka mokhoa oa ho hlahisa li-amine tsa chiral le joala tse nang le stereoselectivity e phahameng. Ho feta moo, tert-Butylsulfinamide e bapala karolo ea bohlokoa tlhahisong ea li-sulfinamides tsa chiral, tse sebetsang e le li-intermediate tsa bohlokoa liphetohong tse fapaneng tsa lik'hemik'hale. Bokhoni ba eona ba ho fana ka taolo ea stereochemical bo lebisitse tšebelisong e pharaletseng ea li-agent tsa meriana, lihlahisoa tsa tlhaho le thepa e tsoetseng pele. Ho feta moo, nts'etsopele ea mekhoa e mecha ea maiketsetso e kenyeletsang tert-Butylsulfinamide e ntse e tsoela pele ho atolosa ts'ebeliso ea eona lefapheng la k'hemistri ea lintho tse phelang. Ho tloha liphetohong tse sa lekanang tsa catalytic ho ea tlhahisong ea li-block tse rarahaneng tsa kaho, reagent ena e ntse e le lejoe la motheo la ho phehella tlhahiso ea lik'hemik'hale e sebetsang hantle le e khethollang. Ka bokhutšoanyane, tert-Butylsulfinamide e eme e le sesebelisoa sa bohlokoa bakeng sa litsebi tsa lik'hemik'hale tse batlang ho fumana metsoako ea enantiopure ka stereochemistry e etselitsoeng motho ka mong. Tšusumetso ea eona e akaretsa masimo a ho sibolloa ha lithethefatsi, tlhahiso ea lik'hemik'hale le saense ea lintho tse bonahalang, e totobatsa bohlokoa ba eona e le reagent e feto-fetohang le e matla k'hemistring ea sejoale-joale ea lintho tse phelang.