(S)-tert-Butyl 2-methylaziridine-1-carboxylate CAS:197020-60-3

(S)-tert-Butyl 2-methylaziridine-1-carboxylate e bapala karolo ea bohlokoa e le mokena-lipakeng oa metsoako e rarahaneng, e sebetsang ka lintho tse phelang e nang le lits'ebetso tse ka bang teng tsa meriana. Ho kenyelletsoa ha eona meralong ea limolek'hule ho nolofalletsa bafuputsi ho hlahloba bakhethoa ba meriana ba bacha ba shebaneng le libaka tsa kalafo tse kang li-antitumor agents, li-enzyme inhibitors, kapa li-chiral building blocks bakeng sa tlhahiso ea meriana. Boteng ba chiral aziridine core bo hlahisa reactivity e itseng le thepa ea pharmacophoric, e leng se etsang hore e be ea bohlokoa bakeng sa lipatlisiso tsa k'hemistri ea meriana. Maitekong a ho sibolla lithethefatsi, motsoako ona o ka sebetsa e le sebaka sa ho qala ho rala bakhethoa ba meriana ba ka bang teng, o sebelisa likarolo tsa oona tsa sebopeho ho fetola ts'ebetso ea baeloji le thepa ea pharmacokinetic. Ho feta moo, tlhaho ea chiral ea molek'hule e ka susumetsa likamano tsa eona le lipheo tsa baeloji, e ka amang thepa ea eona ea pharmacological le ho ntlafatsa ts'ebeliso ea eona nts'etsopele ea lithethefatsi. Ho feta moo, libakeng tsa thuto le tsa indasteri, bafuputsi ba ka sebelisa motheo ona oa kaho ho lokisa lilaebrari tsa lintho tse fapaneng tse tsoang ho tsona bakeng sa lithuto tsa kamano ea sebopeho le ts'ebetso, ho nolofalletsa ho tsebahatsa metsoako ea loto e nang le litlamorao tse lakatsehang tsa baeloji. Karolo ea eona tlhahisong ea lik'hemik'hale e atolohela tlhahisong ea li-intermediate tsa meriana le nts'etsopele ea mekhoa e mecha ea maiketsetso, e bonts'a ts'ebeliso ea eona e pharaletseng mafapheng a saense. Ka kakaretso, (S)-tert-Butyl 2-methylaziridine-1-carboxylate e bapala karolo ea bohlokoa ho sibolloeng ha meriana e mecha le lipatlisisong tsa lik'hemik'hale, e fana ka sethala sa nts'etsopele ea limolek'hule tse fapaneng tse sebetsang ka baeloji le metsoako e mahareng ea meriana.