Rosuvastatin Calcium CAS:147098-20-2 Mofani oa Moetsi

Khalsiamo ea Rosuvastatin ke thibelo e khethiloeng ea HMG-CoA reductase. HMG-CoA reductase inhibitor ke enzyme e fokotsang sekhahla sa phetoho ea hydroxy-3-methylglutaryl coenzyme A ho valerate A (E leng selelekela sa k'holeseterole). Sebaka se seholo sa ts'ebetso ea rosuvastatin ke sebete - litho tse reretsoeng ho fokotsa k'holeseterole. Rosuvastatin e eketsa palo ea li-receptor tsa LDL sebeteng holim'a sele, e khothaletsa ho monngoa le ho hatelloa ha LDL, e thibela tlhahiso ea VLDL sebeteng, ka hona e fokotsa palo eohle ea likaroloana tsa VLDL le LDL. Khalsiamo ea Rosuvastatin e khona ho thibela sebete sa methylglutaryl coenzyme A reductase ka tlholisano, 'me e boetse e sebelisa phello ea eona e ntle ho fokotseng mafura. E na le halofo ea bophelo bo bolelele. Bong le lilemo tsa bakuli ha li na tšusumetso e kholo metabolism ea lithethefatsi.