Rosuvastatin Calcium CAS:147098-20-2 Mofani oa Moetsi

Rosuvastatin calcium ke inhibitor e ikhethileng ea HMG-CoA reductase.HMG-CoA reductase inhibitor ke enzyme e fokotsang sekhahla sa phetoho ea hydroxy-3-methylglutaryl coenzyme A ho valerate A (Selelekela sa k'holeseterole).Sebaka sa mantlha sa ts'ebetso ea rosuvastatin ke sebete - litho tse reretsoeng ho theola k'holeseterole.Rosuvastatin e eketsa palo ea li-receptor tsa LDL ka holim'a sele, e khothalletsa ho monya le catabolism ea LDL, e thibela tlhahiso ea sebete ea VLDL, ka hona e fokotsa palo eohle ea likaroloana tsa VLDL le LDL. Rosuvastatin calcium e khona ho thibela ka tlholisano ho thibela sebete methylglutaryl coenzyme A , 'me ho feta moo e fana ka phello ea eona e ntle ho fokotsa mafura.E na le halofo ea bophelo bo bolelele.Tekano le lilemo tsa bakuli ha li na phello e kholo metabolism ea lithethefatsi.