(R)-tert-Butyl 2-(2-hydroxyethyl)piperazine-1-carboxylate CAS:947275-74-3

Tšebeliso e nang le mahlakore a mangata ea (R)-tert-Butyl 2-(2-hydroxyethyl)piperazine-1-carboxylate e bonahala lits'ebetsong tsa eona lipatlisisong tsa meriana le ho sibolloa ha meriana. E le motheo oa chiral, e bapala karolo ea bohlokoa nts'etsopele ea limolek'hule tse ncha tsa tlhaho le bakhethoa ba meriana ba ka bang teng. Bafuputsi ba ka sebelisa likarolo tsa eona tsa sebopeho ho hlahloba karolo ea eona ho nts'etsopele ea mekhoa ea phekolo e shebaneng le mafu a fapaneng, e leng se ka lebisang ho thehoeng ha lihlahisoa tse ncha tsa meriana tse nang le katleho e ntlafalitsoeng le thepa e ntlafalitsoeng ea pharmacokinetic, e fanang ka melemo e ka bang teng bakeng sa tlhokomelo ea bophelo bo botle le meriana. Ho feta moo, motsoako ona oa chiral o sebelisoa ho tsoakoeng ha tlhaho, o nolofalletsang ho thehoa ha limolek'hule tse rarahaneng tsa tlhaho tse hlokahalang bakeng sa lits'ebetso tse fapaneng tsa indasteri. Litšobotsi tsa eona tsa sebopeho li etsa hore e be ea bohlokoa bakeng sa ho kopanngoa ha lik'hemik'hale tse ntle, lik'hemik'hale tsa temo le thepa e sebelisoang makaleng a mangata, e tlatsetsang katolosong ea sebaka sa lik'hemik'hale se fumanehang bakeng sa nts'etsopele ea sehlahisoa le lits'ebetso tsa indasteri. Ho feta moo, (R)-tert-Butyl 2-(2-hydroxyethyl)piperazine-1-carboxylate e tšehetsa ho hlahlojoa ha liketso tse ncha tsa lik'hemik'hale le nts'etsopele ea litsela tse ncha tsa maiketsetso, e fa bafuputsi le litsebi tsa lik'hemik'hale sesebelisoa se feto-fetohang bakeng sa ho theha meaho e mecha ea limolek'hule. Tšebeliso ea eona e nang le mahlakore a mangata e totobatsa karolo ea eona ea bohlokoa ho khanneng boqapi le tsoelo-pele ka har'a tlhahiso ea lintho tse phelang, lipatlisiso tsa meriana, le indasteri e pharaletseng ea lik'hemik'hale, e fana ka litsela tse tšepisang bakeng sa nts'etsopele ea lihlahisoa le mahlale a macha. Ka kakaretso, lits'ebetso tse feto-fetohang tsa motsoako ona li o beha e le letlotlo la bohlokoa lipatlisisong tsa mahlale le mesebetsing ea indasteri.