R-(+)-alpha-Lipoic acid CAS:1200-22-2 Mofani oa Moetsi

Asiti ea R-(+)-α-Lipoic e bontšitsoe e eketsa haholo oxidation ea pyruvate ha e ntse e tlosa oxidation ea mafura a acid ho li-hepatocyte tsa rat. Litlamorao tsena li etsa hore R-(+)-α-Lipoic acid e be khetho e tšepisang ea kalafo bakeng sa kalafo ea lefu la tsoekere la Mofuta oa II. Ke antioxidant ea baeloji e nang le mesebetsi ea prooxidant, bokhoni ba eona ba kalafo bo hlahlojoa haholo, mohlala, kalafong ea lefu la Alzheimer. α-Lipoic acid e sebelisitsoe e le tekanyetso ea litšupiso bakeng sa tlhahlobo ea α-lipoic acid plasma ea motho ka chromatography ea metsi e sebetsang hantle e kopantsoeng le detector ea ho hapa li-electron (HPLC-ECD), ka har'a matrices e fapaneng ea lijo le li-supplement tsa lijo ka HPLC e kopantsoeng le coulometric electrode array detector (CEAD) hammoho le electrospray ionization mass spectrometer (ESI-MS). E ka sebelisoa e le tekanyetso ea litšupiso bakeng sa ho fumana α-lipoic acid ka morotong oa motho ka isocratic reversed-phase HPLC le ka har'a li-capsules tsa α-lipoic acid ka HPLC ka ho lemoha chemiluminescence.