Pyridoxal-5′-phosphate monohydrate CAS:41468-25-1

Pyridoxal-5′-phosphate monohydrate, e tsejoang hape e le PLP, ke mofuta o sebetsang oa vithamine B6. Ke coenzyme ea bohlokoa e amehang liketsong tse fapaneng tsa enzymatic 'meleng. PLP e bapala karolo ea bohlokoa ho metabolism ea amino acid, tlhahiso ea neurotransmitter, le tlhahiso ea heme, karolo ea hemoglobin.

PLP e sebetsa e le coenzyme ka ho tlama dienzyme tse itseng le ho thusa dikarabelong tsa dikhemikhale. E sebetsa e le catalyst, e thusa ho fetola dintho tse fapaneng, tse kang di-amino acid, hore e be dihlahiswa tse fapaneng. PLP e bohlokwa haholo ho metabolism ya di-amino acid, jwalo ka ho fetola tryptophan hore e be serotonin, kapa ho senyeha ha glycine hore e be serine.

Ntle le karolo ea eona ho metabolism ea amino acid, PLP e boetse e ameha ho qaptjoeng ha li-neurotransmitter tse kang dopamine, norepinephrine, le gamma-aminobutyric acid (GABA). Li-neurotransmitter tsena li bohlokoa bakeng sa ts'ebetso e nepahetseng ea boko 'me li ameha taolong ea maikutlo, kutloisisong, le phetisong ea matšoao lipakeng tsa lisele tsa methapo.

Ho feta moo, PLP ea hlokahala bakeng sa ho etsoa ha heme, e leng karolo ea hemoglobin e fumanoang liseleng tse khubelu tsa mali. Hemoglobin e ikarabella bakeng sa ho jara oksijene ho pholletsa le 'mele, e leng se etsang hore PLP e be ea bohlokoa bakeng sa ho boloka maemo a tloaelehileng a oksijene le ho netefatsa ts'ebetso e nepahetseng ea litho le lisele tse fapaneng.

Ka lebaka la bohlokoa ba eona lits'ebetsong tse ngata tsa biochemical, tlatsetso ea PLP ka linako tse ling e khothaletsoa batho ba nang le maemo a itseng a bongaka kapa mefokolo e amang metabolism ea vithamine B6. E fumaneha ka mokhoa oa tlatsetso 'me e ka laeloa ke bafani ba tlhokomelo ea bophelo bakeng sa litlhoko tse itseng.