Puromycin dihydrochloride CAS: 58-58-2 Theko ea moetsi

Puromycin dihydrochloride ke sebolaya-mafu se matla se sebediswang haholo dipatlisisong tsa baeloji ya dimolek'hule le baeloji ya disele. E thibela tlhahiso ya protheine ka ho baka ho kgaotsa ho etswa ha protheine pele ho nako nakong ya phetolelo. Puromycin e sebetsa ka ho etsisa pheletso ya 3' ya molek'hule ya tRNA e nang le aminoacylated mme e kenngwa ka hara ketane ya protheine e ntseng e hola. Sena se lebisa ho kgaoleng ha protheine mme qetellong se emisa tshebetso ya phetolelo.

Tšebeliso e ka sehloohong ea puromycin dihydrochloride ke ho khethong le ho aroleng lisele tse fetotsoeng liphatsa tsa lefutso kapa tse fetotsoeng ka gene ea ho hanyetsa puromycin. Sena se finyelloa ka ho hlahisa gene e khahlisang hammoho le gene ea ho hanyetsa puromycin liseleng, ebe li li beha kalafong ea puromycin. Ke lisele feela tse kentseng ka katleho gene ea ho hanyetsa puromycin ka har'a genome ea tsona tse tla pholoha le ho ata, e leng se lumellang khetho le ho aroloa ha lisele tse lakatsehang.

Puromycin dihydrochloride e boetse e sebelisoa lithutong tse amanang le tlhahiso ea liphatsa tsa lefutso le tlhahiso ea protheine. Ka ho thibela tlhahiso ea protheine, e ka thusa bafuputsi ho ithuta matla a tlhahiso ea protheine, ho khetholla liprotheine tse itseng tse hlahisoang ka potlako ho arabela linthong tse itseng tse susumetsang, le ho sekaseka mekhoa ea phetolelo.

Ho feta moo, puromycin dihydrochloride e sebediswa ho hlahisa mela e tsitsitseng ya sele e nang le diphetoho tse ikgethang tsa lefutso. Ka ho kenyelletsa jini ya ho hanyetsa puromycin hammoho le phetoho ya lefutso e rerilweng, bafuputsi ba ka hlahisa mela ya sele e hlalosang ka botsitso jini ya thahasello le ho hanyetsa puromycin. Sena se dumella dithuto tsa nako e telele le tlhaloso ya tshebetso ya jini.