Protheine Kinase Supplement KT5823 CAS:126643-37-6

Tlatsetso ea protheine kinase KT5823 ke thibelo e nyane ea molek'hule e shebaneng le le ho thibela ts'ebetso ea protheine kinase ka ho khetheha. Li-protein kinase ke li-enzyme tse fosforolang liprotheine ka ho eketsa lihlopha tsa phosphate ho masala a itseng a amino acid, hangata serine, threonine, kapa tyrosine. Ts'ebetso ena ea phosphorylation e bapala karolo ea bohlokoa litseleng tse fapaneng tsa lipontšo tsa sele, ho laola ts'ebetso ea protheine, le ho laola lits'ebetso tsa sele tse kang kholo ea sele, karohano, phapang le apoptosis.

KT5823 e sebediswa hangata diphuputsong tsa dipatlisiso ho fuputsa tshebetso le ditsela tsa ho bontsha dipontsho tsa di-protein kinase. Ka ho thibela di-protein kinase, KT5823 e ka thusa bafuputsi ho fumana diprotheine le ditsela tse itseng tse amehang ke mosebetsi wa kinase. Tlhahisoleseding ena e ka ba le temohisiso ho utlwisiseng karolo ya di-protein kinase mesebetsing ya sele le ho tsebahatsa dipheo tse ntjha tsa kalafo.

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Tšebeliso le Phello

Tlatsetso ea protheine kinase KT5823 ke thibelo e sebelisoang haholo ea protheine kinase G (PKG), e shebaneng haholo le mofuta oa I isoform PKG-1. PKG ke serine/threonine kinase e bapalang karolo ea bohlokoa lits'ebetsong tse fapaneng tsa sele tse kang ho phomola mesifa e boreleli, ho bokellana ha liplatelete le taolo ea vasodilation.

Tšusumetso e ka sehloohong ea KT5823 ke thibelo ea ts'ebetso ea PKG-1 ka ho qothisana lehlokoa le ATP ho domain ea kinase. Ka ho thibela PKG-1, KT5823 e ka sitisa litsela tsa lipontšo tse theohelang ts'ebetsong ea PKG-1, ho kenyeletsoa le li-cascades tsa lipontšo tse itšetlehileng ka cGMP.

Tšebeliso ea KT5823 e haholo-holo lithutong tsa lipatlisiso ho batlisisa mosebetsi le litsela tsa lipontšo tsa PKG-1. Tšebeliso ea eona ho thibeleng mosebetsi oa PKG-1 e lumella bafuputsi ho batlisisa mesebetsi ea PKG-1 lits'ebetsong tse fapaneng tsa 'mele le tsa pathological. Litšebeliso tse ling tse ikhethileng tsa KT5823 li kenyelletsa:

Ho batlisisa ho phomola ha mesifa e boreleli: PKG-1 e bapala karolo ea bohlokoa ho phomoleng ha mesifa e boreleli. Ka ho thibela PKG-1 ho sebelisa KT5823, bafuputsi ba ka ithuta mekhoa le litsela tse ka sehloohong tse amehang ho phomoleng ha mesifa e boreleli, e leng sa bohlokoa masimong a kang lipatlisiso tsa pelo le methapo ea mali.

Ho ithuta ho kopana ha liplatelete: PKG-1 e boetse e laola ho kopana ha liplatelete le ho thehoa ha maqeba. Ho thibela PKG-1 ka KT5823 ho lumella bafuputsi ho lekola tšusumetso ea ts'ebetso ea PKG-1 mosebetsing oa liplatelete le ho utloisisa litsela tse amehang.

Ho hlahloba lipheo tse theohelang tsa PKG-1: Ka ho thibela PKG-1, bafuputsi ba ka tseba le ho ithuta lipheo tse theohelang le tse susumetsang lipontšo tsa PKG-1, ba fana ka temohisiso mabapi le mekhoa ea limolek'hule e thehiloeng likarabong tsa sele tse tsamaisoang ke PKG-1.

Ho paka Sehlahisoa:

Tlhahisoleseling e 'Ngoe:

Sebopeho	C29H25N3O5
Teko	99%
Ponahalo	Phofo e tšoeu
Nomoro ea CAS	126643-37-6
Ho paka	E nyane le e ngata
Bophelo ba Shelofo	lilemo tse 2
Polokelo	Boloka sebakeng se pholileng le se omileng
Setifikeiti	ISO.