Letrozole ke karolo ea moloko o mocha oa li-aromatase inhibitors tse khethang haholo 'me ke motsoako oa maiketsetso oa benzotriazole.Letrozole e thibela aromatase ho theola maemo a estrogen, kahoo e thibela estrogen ho susumetsa kholo ea hlahala.Ts'ebetso ea eona ea in vivo e matla ka makhetlo a 150-250 ho feta ea moloko oa pele oa aromatase inhibitor Amarante.Kaha e khetha haholo, e ke ke ea ama glucocorticoid, mineralocorticoid le mesebetsi ea qoqotho;esita le ka litekanyetso tse phahameng, e ke ke ea e-ba le liphello tse thibelang li-adrenal corticosteroid secretion, e fanang ka index e phahameng ea phekolo.