Nitrocefin CAS:41906-86-9

Lilaboratoring tsa microbiology tsa kliniki, nitrocefin e sebelisoa ho leka likaroloana tsa baktheria bakeng sa tlhahiso ea li-enzyme tsa beta-lactamase, tse fanang ka khanyetso khahlanong le lithibela-mafu tsa beta-lactam. Teko e kenyelletsa ho eketsa nitrocefin ho setso sa baktheria kapa ka ho toba koloneng ea likokoana-hloko lipoleiting tsa agar. Haeba libaktheria li hlahisa beta-lactamase, hydrolysis ea nitrocefin e fella ka phetoho ea 'mala ho tloha mosehla ho ea bofubelu ka metsotso e seng mekae, e leng se bontšang boteng ba enzyme. Teko ea nitrocefin e molemo haholo bakeng sa ho khetholla pakeng tsa mefuta ea libaktheria tse hlahisang beta-lactamase le tse sa hlahiseng, e thusang ho khethoeng ha phekolo e nepahetseng ea lithibela-mafu. Liphetho tse ntle li bontša hore libaktheria li hanela lithibela-mafu tsa beta-lactam, e leng se susumetsang tšebeliso ea li-agent tse ling tsa lithibela-mafu. Ka lehlakoreng le leng, liphetho tse mpe li bontša ho hanela lithibela-mafu tsa beta-lactam, e leng se tataisang lingaka ho khetheng likhetho tse sebetsang tsa kalafo. Ka lebaka la bonolo le ho potlaka ha eona, teko ea nitrocefin e sebelisoa hangata lilaboratoring tsa kliniki bakeng sa liteko tsa kamehla tsa ho hanela lithibela-mafu le merero ea taolo ea tšoaetso. E fana ka tlhahisoleseling ea bohlokoa ho bafani ba tlhokomelo ea bophelo bakeng sa ho ntlafatsa phekolo ea lithibela-mafu le ho thibela ho ata ha libaktheria tse hanela lithibela-mafu libakeng tsa tlhokomelo ea bophelo. Mehato e nepahetseng ea taolo ea boleng le litataiso tsa tlhaloso li bohlokoa ho netefatsa ho nepahala le ho tšepahala ha liphetho tsa liteko tsa nitrocefin, tse tlatsetsang tsamaisong e atlehang ea bakuli le boitekong ba ho laola likokoana-hloko.