N-methyl-2,2,2-trifluoroacetamide CAS:815-06-5

N-Methyl-2,2,2-trifluoroacetamide (NMTFA) e khetholloa ka sebopeho sa eona sa limolek'hule, se kenyeletsang sehlopha sa trifluoromethyl (-CF3) se hoketsoeng mokokotlong oa acetamide (-CONHCH3). Sebopeho sena se fana ka botsitso bo boholo le karabelo ho NMTFA, e leng se etsang hore e lokele mefuta e mengata ea lits'ebetso tsa lik'hemik'hale. Hangata NMTFA e teng e le kristale e tiileng e nang le ntlha ea ho qhibiliha ea hoo e ka bang 62°C 'me e bontša ho qhibiliha ho hotle litharollong tsa polar organic tse kang acetone le ethanol. Ho tsitsa ha eona tlas'a maemo a fapaneng ho lumella tšebeliso ea eona e sebetsang lipatlisisong tsa laboratori le lits'ebetsong tsa indasteri. Tšebeliso ea Organic Synthesis: NMTFA e sebetsa e le mokena-lipakeng oa bohlokoa ho etseng lintho tse phelang, haholo-holo ho kenyelletsoeng ha lihlopha tsa trifluoromethyl ka har'a limolek'hule tsa organic. Bokhoni bona bo bohlokoa bakeng sa ho nts'etsapele meriana, lik'hemik'hale tsa temo, le lik'hemik'hale tse ikhethang tse nang le ts'ebetso e ntlafalitsoeng ea baeloji le botsitso ba lik'hemik'hale. Khemistri ea Meriana: Litšebelisong tsa meriana, NMTFA e sebelisoa e le selelekela ho etseng metsoako e sebetsang ea meriana (APIs) ka lebaka la bokhoni ba eona ba ho fana ka thepa e lakatsehang ea meriana. E bapala karolo ea bohlokoa k'hemistring ea meriana ka ho nolofalletsa phetoho ea limolek'hule tsa meriana ho ntlafatsa katleho le ho fokotsa ho pepesehela metabolism. Lik'hemik'hale tse Ikhethang: NMTFA e fumana ts'ebeliso tlhahisong ea lik'hemik'hale tse ikhethang tse kang li-surfactants, li-plasticizer, le li-intermediate tse rarahaneng tse sebelisoang tlhahisong ea lik'hemik'hale tsa temo le lik'hemik'hale tse ntle. Ho feto-fetoha ha eona liphetohong tsa lik'hemik'hale ho e etsa ea bohlokoa mefuteng moo ho hlokahalang taolo e nepahetseng holim'a sebopeho le ts'ebetso ea limolek'hule. Ho kopanngoa ha N-Methyl-2,2,2-trifluoroacetamide ho etsoa ka karabelo ea trifluoroacetic acid le methylamine. Ts'ebetso ena e kenyelletsa ho koaheloa ha trifluoroacetic acid le methylamine tlas'a maemo a laoloang ho theha NMTFA. Hangata karabelo e tsoela pele ka boteng ba catalyst e loketseng ho nolofalletsa ho thehoa ha amide bond. Mekhoa ea ho hloekisa joalo ka recrystallization kapa chromatography e sebelisoa ho fumana NMTFA e hloekile haholo e loketseng lits'ebetso tsa indasteri. Mokhoa o bonolo oa ho kopanya le ho fumaneha ha thepa e tala ho tlatsetsa ho katlehong ea eona ea litšenyehelo le ts'ebeliso e pharaletseng lipatlisisong tsa thuto le lits'ebetsong tsa indasteri. Ka bokhutšoanyane, N-methyl-2,2,2-trifluoroacetamide ke motsoako o feto-fetohang o nang le ts'ebeliso ea bohlokoa tlhahisong ea lintho tse phelang, k'hemistri ea meriana, le tlhahiso ea lik'hemik'hale tse ikhethang. Litšobotsi tsa eona tse ikhethang tsa lik'hemik'hale, ho kenyeletsoa botsitso, karabelo, le bonolo ba tlhahiso, li kenya letsoho bohlokoa ba eona ho ntšetseng pele mahlale a theknoloji makaleng a fapaneng a indasteri le mafapheng a saense.