N-Acetyl-L-proline amide CAS:16395-58-7

N-Acetyl-L-proline amide e sebelisoa haholo k'hemistring ea peptide e le karolo ea bohlokoa bakeng sa ho kopanya li-peptide le li-peptidomimetics. Jwalo ka proline derivative ea acetylated, e sebetsa e le intermediate e feto-fetohang bakeng sa ho kenya motifs e itseng ea sebopeho kapa lihlopha tse sebetsang ka har'a liketane tsa peptide ka mekhoa ea ho kopanya peptide ea mohato o tiileng le mohato oa tharollo. Bafuputsi le litsebi tsa lik'hemistri ba sebelisa N-Acetyl-L-proline amide ho etsa hore tatellano ea li-peptide e be le thepa e ikhethileng, e nolofalletsang nts'etsopele ea metsoako e mecha ea bioactive le li-peptide tsa kalafo tse shebaneng le li-receptor, li-enzyme, kapa li-transporter litsamaisong tsa baeloji. Ho feta moo, N-Acetyl-L-proline amide e sebelisoa tlhahisong ea li-intermediate tsa meriana, moo sebopeho sa eona sa lik'hemik'hale le botsitso li tlatsetsang ho kopanyeng ha metsoako ea bioactive le baemeli ba meriana. Ho feto-fetoha ha eona le botšepehi ba eona ho e etsa ea bohlokoa tlhahisong ea lihlahisoa tsa meriana, ho ntlafatsa thepa ea meriana le ts'ebetso ea baeloji ea bakhethoa ba ho qetela ba meriana. Ho feta moo, N-Acetyl-L-proline amide e sebelisoa lipatlisisong tsa biochemical ho ithuta metabolism ea proline, ts'ebetso ea protheine le kinetics ea enzyme. Karolo ea eona ho hlakiseng litsela tsa sele le lits'ebetso tsa metabolism e thusa ho utloisisa mesebetsi ea proline lits'ebetsong tsa baeloji le litlamorao tsa eona tse ka bang teng bophelong bo botle le mafung. Ka bokhutšoanyane, N-Acetyl-L-proline amide e bapala karolo ea bohlokoa ho ntšetseng pele lipatlisiso tsa mahlale, nts'etsopele ea meriana le lithuto tsa biochemical, e fa bo-rasaense le litsebi sesebelisoa se feto-fetohang sa ho hlahloba lits'ebetso tse fapaneng tsa li-derivatives tsa proline ho sibolloeng ha lithethefatsi, ho hlophisoa ha peptide le lipatlisiso tsa biochemical.