Losartan Potassium CAS: 124750-99-8 Mofani oa Moetsi

Losartan potassium ke mohanyetsi oa pele oa AT1 receptor ea angiotensin II (AT II) ea matla le e khethang e hlahisitsoeng 'marakeng e le moriana o thibelang khatello ea mali o nooang hang ka letsatsi. E sebetsa hantle ebile e nka nako e telele ho laoleng khatello ea mali ho likhoto tse nang le khatello ea mali e sa reroang, ho bakuli ba nang le khatello ea mali e kholo hammoho le bakuli ba nang le bothata ba liphio. Ntle le moo, phuputso ea morao tjena e bontšitse hore losartan e molemo ho khutlisetsa morao ho se sebetse hantle ho amanang le botsofali ho bolokeng khatello ea mali e tloaelehileng le tšebeliso ea matla a sele ho mitochondria 'me mohlomong e ka sebelisoa ho phekola hypertrophy ea ventricular e letšehali. E ka boela ea sebelisoa e le moemeli o mong bakeng sa kalafo ea ho se sebetse hantle ha systolic, infarction ea myocardial, lefu la methapo ea pelo le ho hloleha ha pelo.