Ibandronate Sodium CAS: 138844-81-2 Mofani oa Moetsi

Ibandronate sodium e 'nile ea sebelisoa ho ithuta phello ea eona ho ata le ultrastructure ea Leishmania le Giardia ka moloko oa li-curves tsa mahloriso.E boetse e sebelisetsoa ho hlakisa tsela eo ka eona li-bisphosphonates tse nang le naetrojene (N-BPs) li kenang cytosol le ho thibela sepheo sa tsona sa molek'hule.Ibandronate sodium e thibela farnesyl diphosphate synthase (IC50 = 20 nM).Ibandronate sodium e boetse ke lesapo resorption inhibitor.E 'nile ea batlisisoa bakeng sa litlamorao tsa in vitro anti-tumor, joalo ka ho kenngoa ha apoptosis, inhibitor ea kholo ea lisele, thibelo ea boits'oaro bo hlaselang, le thibelo ea angiogenesis le karolo ea eona ea in vivo mefuteng e fapaneng ea mofetše ho kenyelletsa mofetše oa matsoele le oa senya.