Hydroxyprogesteroneacetate CAS:302-23-8

Hydroxyprogesteroneacetate e sebelisoa maemong a fapaneng a bongaka ka lebaka la thepa ea eona ea progestogenic le litlamorao tsa meriana. Lipetleleng tsa pelehi le tsa basali, e laetsoe ho thibela tsoalo ea pele ho nako ho basali ba kotsing ea ho pepa pele ho nako. Ka ho susumetsa tikoloho ea popelo le mokhoa oa ho butsoa ha popelo, Hydroxyprogesteroneacetate e thusa ho fokotsa monyetla oa ho pepa pele ho nako le ho ntlafatsa liphello tsa masea a sa tsoa tsoaloa. Ho feta moo, phekolong ea phetolo ea lihormone (HRT), Hydroxyprogesteroneacetate e fanoa ho fokotsa matšoao a ho khaotsa ho ilela khoeli le ho leka-lekanya maemo a lihormone. E etsisa liketso tsa progesterone ea tlhaho, e tšehetsa bophelo bo botle ba endometrial le ho thibela kholo e sa tloaelehang ea popelo. Kalafo ena ea lihormone e bohlokoa bakeng sa ho laola maemo a kang matšoao a vasomotor a ho khaotsa ho ilela khoeli, osteoporosis ea postmenopausal, le tšireletso ea endometrial kalafong ea estrogen. Ho feta moo, Hydroxyprogesteroneacetate e sebelisoa kalafong ea mathata a itseng a basali, joalo ka ho tsoa mali ho sa tloaelehang ha popelo, amenorrhea, le polycystic ovary syndrome (PCOS). Bokhoni ba eona ba ho laola potoloho ea ho ilela khoeli le ho khothaletsa ho ovulation kamehla bo e etsa hore e be molemo ho sebetsana le mathata a bophelo bo botle ba ho ikatisa le matšoenyeho a ho ba le bana. Ho phaella moo, Hydroxyprogesteroneacetate e ka sebediswa mmoho le meriana e meng bakeng sa merero ya thibelo ya bokhachane kapa kankere e utlwang dihormone ho laola tshebetso ya di-receptor tsa dihormone. Ka kakaretso, ditshebediso tse pharaletseng tsa Hydroxyprogesteroneacetate bophelong bo botle ba basadi, meriana ya ho ikatisa le mathata a endocrine di totobatsa bohlokwa ba yona e le sehlahiswa sa bohlokwa sa meriana se nang le tshebediso e fapaneng ya kalafo. Karolo ya yona ho bolokeng botsitso ba dihormone, ho tshehetsa boimana, le ho laola maemo a basadi e totobatsa bohlokwa ba yona mekgweng ya sejwalejwale ya tlhokomelo ya bophelo.