HD-Arg(NO2)-OMe·HCl CAS:50912-92-0

HD-Arg(NO2)-OMe·HCl e bohlokoa lithutong tsa biochemical le tsa sele ka lebaka la bokhoni ba eona ba ho etsisa liphetoho tse itseng tsa liprotheine kamora phetolelo. Bafuputsi ba sebelisa motsoako ona oa maiketsetso ho batlisisa litlamorao tsa methoxylation le nitration mesebetsing ea protheine, litsela tsa lipontšo tsa sele, le mekhoa ea mafu. Libakeng tsa laboratori, HD-Arg(NO2)-OMe·HCl e sebelisoa ho lekola tšusumetso ea eona ts'ebetsong ea enzyme, likamano tsa protheine le protheine, le li-cascades tsa lipontšo tsa ka hare ho sele. Ho feta moo, ts'ebeliso ea eona e atolohela ho ithuteng ho kenella ha methoxylation le nitration lits'ebetsong tsa 'mele le maemo a pathological, e fana ka temohisiso e amanang le mekhoa e ka bang teng ea kalafo. Tšebeliso ea HD-Arg(NO2)-OMe·HCl e thusa ho ntlafatsa kutloisiso ea rona ea taolo ea sele, likarabo tsa khatello ea oxidative, le tsoelo-pele ea mafu. Ho tenyetseha ha eona ho nolofalletsa bo-rasaense ho hlahloba mekhoa e rarahaneng ea limolek'hule e thehiloeng lits'ebetsong tse fapaneng tsa baeloji, ho fana ka tlhahisoleseling ea bohlokoa e nang le litlamorao bakeng sa saense ea motheo le lipatlisiso tsa kliniki. Ka lebaka leo, motsoako ona oa maiketsetso o emela sesebelisoa sa bohlokoa bakeng sa bafuputsi ba batlang ho rarolla mathata a ts'ebetso ea sele le litsela tsa ho fana ka matšoao, ka hona ba khanna tsoelo-pele lipatlisisong tsa bongaka, ho sibolloa ha meriana le mekhoa e ka bang teng ea phekolo.