-
2′-O-Methyluridine CAS:2140-76-3 Theko ea moetsi
2′-O-Methyluridine ke nucleoside e fetotsoeng e nang le sehlopha sa methyl sebakeng sa 2′ sa lesale la ribose. Ke motheo oa bohlokoa oa ho kopanya limolek'hule tsa RNA tse fetotsoeng 'me e ithutiloe bakeng sa litšobotsi tsa eona tse ka bang teng tsa baeloji le tsa meriana. Tse ling tsa lits'ebetso tsa eona tse tlalehiloeng li kenyelletsa ts'ebeliso ea eona lipatlisisong tsa RNA, e le karolo tlhahisong ea RNA e fetotsoeng bakeng sa lits'ebetso tsa genomics tsa kalafo le tse sebetsang, le e le sesebelisoa thutong ea sebopeho le ts'ebetso ea RNA.
-
4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one CAS:951-77-9
2′-Deoxycytidine ke nucleoside e entsoeng ka nucleobase cytosine e hokahaneng le deoxyribose ea tsoekere. Ke karolo ea bohlokoa ea DNA 'me e bapala karolo ea bohlokoa polokelong le phetisong ea tlhahisoleseling ea liphatsa tsa lefutso ka har'a lintho tse phelang.
-
Cytidine-5′-monophosphate (CMP), asiti e lokolohileng CAS:63-37-6
Cytidine 5'-monophosphate (CMP) ke nucleotide e sebetsang e le motheo oa ho haha le ho fetola RNA. Ke karolo ea bohlokoa kahong ea limolek'hule tsa RNA 'me e ameha lits'ebetsong tse kang ho koahela mRNA le metabolism ea nucleotide. CMP e boetse e sebelisoa lipatlisisong tsa biochemical le biology ea limolek'hule bakeng sa lits'ebetso tse kang ho ngoloa ha in vitro le ho ngola li-nucleic acid. Karolo ea eona metabolism ea RNA le ts'ebeliso ea eona mekhoeng e fapaneng ea liteko e etsa hore e be sesebelisoa sa bohlokoa ho utloisiseng sebopeho le ts'ebetso ea limolek'hule tsa RNA.
-
IBMX, 3-isobutyl-1-methylxanthine CAS:28822-58-4
3-isobutyl-1-methylxanthine, e tsejoang hape e le IBMX, ke motsoako oa methylxanthine o sebelisoang hangata lipatlisisong tsa saense e le thibelo e seng ea bohlokoa ea li-cyclic nucleotide phosphodiesterases. E tsebahala ka ho eketsa maemo a ka hare ho sele a cyclic AMP (cAMP) le cyclic GMP (cGMP) ka ho thibela ho senyeha ha tsona, e leng se ka fetolang litsela tse fapaneng tsa ho supa lisele.
Ntle le lits'ebetso tsa eona tsa lipatlisiso, IBMX e 'nile ea sebelisoa libakeng tse ling tsa bongaka bakeng sa litlamorao tsa eona tsa bronchodilator le vasodilator. Leha ho le joalo, tšebeliso ea eona merianeng ea batho e lekanyelitsoe.
-
4-Nitrophenyl phosphate disodium letsoai hexahydrate CAS:4264-83-9
4-Nitrophenyl phosphate disodium salt hexahydrate ke motsoako oa lik'hemik'hale o atisang ho sebelisoa lipatlisisong tsa biochemical le tsa meriana. Ke mofuta oa letsoai oa 4-nitrophenyl phosphate, o nang le li-ion tse peli tsa sodium le limolek'hule tse tšeletseng tsa metsi. Motsoako ona o sebelisoa hangata e le substrate bakeng sa liteko tsa phosphatase le thutong ea kinetics ea enzyme.
-
5′-Deoxy-5-fluorocytidine CAS: 66335-38-4
5′-Deoxy-5-fluorocytidine ke analoge ea nucleoside ea maiketsetso e ntseng e fuputsoa ka lebaka la ts'ebetso ea eona e ka bang teng ea ho loantša vaerase, haholo-holo khahlanong le livaerase tsa RNA tse kang vaerase ea hepatitis C (HCV) le livaerase tsa flavi. E sebetsa ka ho sitisa ho ikatisa ha lintho tsa lefutso tsa vaerase, qetellong e thibela bokhoni ba vaerase ba ho ikatisa le ho ata 'meleng.
-
Cytidine-5′-triphosphate (CTP), letsoai la disodium CAS: 652154-13-7
Letswai la disodium la Cytidine-5′-triphosphate (CTP), ke nucleoside triphosphate e sebetsang e le motheo wa ho kopanya RNA. E bapala karolo ya bohlokwa metabolism ya sele mme e bohlokwa bakeng sa phetiso ya tlhahisoleseding ya lefutso ho tloha ho DNA ho ya ho RNA nakong ya ho ngolwa ha disele. CTP e sebediswa haholo dipatlisisong tsa baeloji ya dimolek'hule, haholoholo diphuputsong tse amanang le ho kopanya RNA, tshitiso ya RNA, le ditsamaiso tse ding tse amanang le RNA. Ho feta moo, e sebediswa dikarabelong tsa enzymatic, dithutong tsa metabolism ya nucleotide, le jwalo ka substrate bakeng sa diteko tse fapaneng tsa biochemical. Indastering ya meriana, CTP e ka boela ya ba le ditshebediso tse ka bang teng ntshetsopeleng ya meriana e lwantshang dikokwana-hloko le e lwantshang kankere.
-
ITP, inosine 5′-triphosphate trisodium letsoai CAS:35908-31-7
Letswai la trisodium la Inosine-5′-triphosphate, le atisang ho khutsufatsoa e le ITP-Na3, ke mofuta oa triphosphate oa inosine, nucleoside e bapalang karolo ea bohlokoa lits'ebetsong tse fapaneng tsa baeloji. Motsoako ona ke mofuta oa letsoai, o etsang hore o qhibilihe metsing 'me o loketse ho sebelisoa litekong tsa biochemical le enzymatic, hammoho le lipatlisisong tsa baeloji ea limolek'hule. Letsoai la trisodium la Inosine-5′-triphosphate le sebelisoa bakeng sa ho ithuta likarabelo tsa enzymatic, interconversion ea nucleotide, le joalo ka substrate bakeng sa lienzyme tse itseng. Ts'ebeliso ea lona e boetse e atoloha lithutong tsa analog tsa nucleotide le joalo ka karolo ea ho lokisa metsoako ea nucleotide e sebelisoang mekhoeng ea baeloji ea limolek'hule.
-
5-Bromouracil CAS: 51-20-7 Theko ea moetsi
5-Bromouracil ke analoge ea maiketsetso ea uracil, e leng karolo ea RNA. 5-Bromouracil e ka kenyelletsoa ho li-nucleic acid 'me e ka baka liphetoho ka ho se lumellane hantle le guanine nakong ea ho ikatisa ha DNA. E sebelisoa e le phetoho lipatlisisong tsa liphatsa tsa lefutso ho ithuta sekhahla sa liphetoho le mekhoa.
-
5-Fluoro-2′-deoxyuridine CAS:50-91-9
5-Fluoro-2′-deoxyuridine ke analoge ea nucleoside ea maiketsetso e thibelang tlhahiso ea DNA. E ithutiloe bakeng sa bokhoni ba eona ba ho loantša vaerase le ho loantša hlahala. Ho feta moo, e sebelisoa e le sesebelisoa sa lipatlisiso baelojing ea limolek'hule le biochemistry.
-
Letswai la Cytidine-5′-triphosphate disodium CAS:36051-68-0
Letswai la Cytidine-5′-triphosphate disodium (CTP-Na2) ke nucleoside triphosphate e sebetsang e le lejoe la motheo tlhahisong ea RNA. E bapala karolo ea bohlokoa metabolism ea sele, e sebetsa e le substrate bakeng sa li-polymerase tsa RNA ho transcription le e le mohloli oa matla bakeng sa liketso tse fapaneng tsa enzymatic. CTP-Na2 e atisa ho sebelisoa lipatlisisong tsa biochemical le baeloji ea limolek'hule e le karolo ea liketso tse kenyeletsang tlhahiso ea RNA, phetoho le taolo. Sebopeho sa letsoai la eona la disodium se eketsa ho qhibiliha ha eona litharollong tsa metsi, e leng se etsang hore e be bonolo haholoanyane bakeng sa tšebeliso ea laboratori.
-
Asiti ea Ribonucleic e tsoang ho Baker's Yeast CAS:63231-63-0
Asiti ea ribonucleic (RNA) e tsoang ho tomoso ea Baker, e tsejoang hape e le Saccharomyces cerevisiae, e bolela limolek'hule tsa RNA tse teng ho fungus ena e tloaelehileng ea sele e le 'ngoe. E sebeletsa mesebetsi e fapaneng ea bohlokoa ka har'a sele, ho kenyeletsoa tlhahiso ea protheine, ts'ebetso ea enzymatic, le taolo ea liphatsa tsa lefutso. RNA e tsoang ho tomoso ea Baker e khahla bo-rasaense le bafuputsi ba ithutang baeloji ea limolek'hule, liphatsa tsa lefutso le lits'ebetso tsa sele. E sebelisoa litekong le lithutong tse fapaneng ho fumana temohisiso mabapi le tlhahiso ea liphatsa tsa lefutso, ts'ebetso ea RNA, le mekhoa ea limolek'hule e thehiloeng mesebetsing ea sele.
