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1 '1-Bis(diphenylphosphino)ferrocene Palladium(Ⅱ)chloride dichloromethane chloride CAS:95464-05-4
1,1-Bis(diphenylphosphino)ferrocene Palladium(II) Chloride Dichloromethane Complex, e nang le foromo ya dikhemikhale [Pd(dppf)Cl₂·CH₂Cl₂], ke motsoako wa organometallic o nang le palladium(II) e hokahantsweng le dppf ligand le dichloride ka hara solvent ya dichloromethane. E sebediswa hangata ho etseng le ho tjhentjha ha dikhemikhale.
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N-(6-bromopyridin-2-yl)thiourea CAS:439578-83-3
N-(6-Bromopyridin-2-yl)thiourea ke motsoako oa lik'hemik'hale o khetholloang ke boteng ba sehlopha se sebetsang sa thiourea se hoketsoeng karolong ea 6-bromopyridin-2-yl. Motsoako ona o hapile thahasello k'hemistring ea meriana ka lebaka la mesebetsi ea oona e fapaneng ea meriana le lits'ebetso tse ka bang teng tsa phekolo. Likarolo tsa oona tse ikhethang tsa sebopeho li fana ka litsela tsa ho rala bakhethoa ba meriana ba bacha ba nang le lipheo tse itseng tsa baeloji, e leng se etsang hore e be letlotlo la bohlokoa ho sibolloeng le nts'etsopele ea meriana.
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2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL CAS:269409-97-4
2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol, e tsejoang haholo e le TMDBP, ke motsoako oa lik'hemik'hale o leng sehlopheng sa li-ester tsa phenolic boronic. Sebopeho sa eona sa limolek'hule se na le sehlopha sa phenolic hydroxyl se hoketsoeng lesale la phenyl le nang le karolo ea ester ea cyclic e nang le boron. Motsoako ona o na le bohlokoa tlhahisong ea lintho tse phelang, haholo-holo liketsong tsa ho kopanya tsa Suzuki-Miyaura, moo o sebetsang e le reagent ea bohlokoa ea boronic ester. Ho feta moo, sebopeho sa eona se tsitsitseng sa boronate ea cyclic le tlhaho e sitisitsoeng ke sterically li etsa hore e be molemo ho raleng ligand bakeng sa liketso tsa phetoho ea tšepe le nts'etsopele ea lisebelisoa tse sebetsang.
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1-Methyl-4-pyrazole boronic acid pinacol ester CAS:761446-44-0
1-Methyl-4-pyrazole boronic acid pinacol ester ke motsoako oa lik'hemik'hale o arotsoeng ka sehlopha sa boronic ester. Sebopeho sa eona sa limolek'hule se entsoe ka karolo ea boronic acid e hoketsoeng lesale la pyrazole e nkeloang sebaka ke sehlopha sa pinacol ester (-OC(CH₃)₂C(CH₃)₂O-). Motsoako ona o na le bohlokoa bo boholo ho etseng lintho tse phelang, haholo-holo liketsong tsa ho kopanya Suzuki-Miyaura, moo o sebetsang e le reagent ea boronic ester e feto-fetohang. Ho feta moo, botsitso ba eona, ts'ebetso e khethiloeng, le ho lumellana le maemo a fapaneng a karabelo ho etsa hore e be ea bohlokoa ho etseng metsoako ea meriana, lik'hemik'hale tsa temo le lisebelisoa tse sebetsang.
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![Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- CAS:1784081-72-6](https://cdn.globalso.com/xindaobiotech/1ZNB2ZF342ZWRNG285.png)
Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- CAS:1784081-72-6
Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- ke motsoako o kopaneng wa bicyclic o nang le sebopeho sa mantlha sa cyclopenta[b]pyrrole le ketane e ka thoko ya hexahydro-1H-pyrrole-3a(1H)-methanol. Molek'hule ena e bohlokwa k'hemistring ya meriana ka lebaka la mesebetsi ya yona e ka bang teng ya meriana. Sebopeho sa yona se ikgethang se fana ka menyetla ya ntshetsopele ya bakgethi ba meriana ba batjha, haholoholo ho shebana le mathata a methapo ya kutlo le mafu a mang moo ho fetolwa ha di-receptor tsa neurotransmitter le di-transporter ho leng bohlokwa. Cyclopenta[b]pyrrole-3a(1H)-methanol, hexahydro- e sebetsa e le scaffold bakeng sa dikhemistri tsa meriana tse hlahlobang di-agent tse ntjha tsa kalafo tse nang le thepa e ntlafetseng ya pharmacokinetic le ditlamorao tse fokotsehileng.
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trans-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylicacid CAS:169248-97-9
Trans-1-(tert-butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid ke molek'hule e rarahaneng e nang le lesale la pyrrolidine le nkeloang sebaka ke sehlopha sa tert-butoxycarbonyl boemong ba 1 le sehlopha sa 3-(trifluoromethyl)phenyl boemong ba 4. Motsoako ona o na le bohlokoa k'hemistring ea meriana, haholo-holo ka lebaka la bokhoni ba oona e le pharmacophore moralong oa lithethefatsi. Sebopeho sa oona se rarahaneng se fana ka menyetla ea ho theha li-agent tse ncha tsa phekolo tse nang le thepa ea meriana e ikhethileng, haholo-holo ho shebana le litsela tse amehang mafung a ho ruruha, mofetše, kapa mathata a tsamaiso ea methapo ea bohareng.
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(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1262849-90-0
(3R,4S)-1-tert-Butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride ke motsoako oa lik'hemik'hale o khetholloang ka lesale la pyrrolidine le nkeloang sebaka ke sehlopha sa ethyl sebakeng sa 3 le sehlopha sa tert-butyl sebakeng sa 1. Motsoako ona o hohetse tlhokomelo k'hemistring ea meriana ka lebaka la sebopeho sa eona sa stereochemical le lits'ebetso tse ka bang teng tsa meriana. Tokisetso ea eona e ikhethang e fana ka litsela tsa ho rala bakhethoa ba meriana ba bacha ba nang le lipheo tse itseng tsa baeloji, e leng se etsang hore e be letlotlo la bohlokoa boitekong ba ho sibolla lithethefatsi le nts'etsopele.
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Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride CAS:1233501-65-9
Cis-1-tert-butyl 3-ethyl 4-aminopyrrolidine-1,3-dicarboxylate hydrochloride ke motsoako oa lik'hemik'hale o khetholloang ke lesale la pyrrolidine le nkeloang sebaka ke sehlopha sa ethyl sebakeng sa 3 le sehlopha sa tert-butyl sebakeng sa 1. Motsoako ona o hapile tlhokomelo k'hemistring ea meriana ka lebaka la ho rarahana ha sebopeho sa oona le ts'ebeliso e ka bang teng ea meriana. Sebopeho sa oona se ikhethang se fana ka menyetla ea ho rala bakhethoa ba meriana ba bacha ba nang le lipheo tse itseng tsa baeloji, e leng se etsang hore e be letlotlo la bohlokoa boitekong ba ho sibolla lithethefatsi le nts'etsopele.
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4-Hydroxyphenylboronic acid pinacol ester CAS: 269409-70-3
4-Hydroxyphenylboronic acid pinacol ester, e tsejoang hape e le 4-HPBA pinacol ester, ke motsoako oa lik'hemik'hale o oelang tlas'a sehlopha sa li-ester tsa boronic. Sebopeho sa eona sa limolek'hule se na le karolo ea boronic acid e hoketsoeng lesale la phenyl le nkeloang sebaka ke sehlopha sa pinacol ester (-OC(CH₃)₂C(CH₃)₂O-). Motsoako ona o na le bohlokoa bo boholo ho etseng lintho tse phelang, haholo-holo liketsong tsa ho kopanya Suzuki-Miyaura, moo o sebetsang e le reagent ea boronic ester e feto-fetohang. Ho feta moo, botsitso ba eona, bonolo ba ho sebetsana le bona, le ho lumellana le maemo a fapaneng a karabelo ho etsa hore e be ea bohlokoa ho etseng metsoako ea meriana, lihlahisoa tsa tlhaho le thepa e sebetsang.
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![Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5](https://cdn.globalso.com/xindaobiotech/HSUS81DS80Y35NTEZTU259.png)
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride CAS:1057260-89-5
Benzyl N-[2-(piperidin-4-yl)propan-2-yl]carbamate hydrochloride ke motsoako oa lik'hemik'hale o nang le sehlopha se sebetsang sa carbamate se hoketsoeng lesale la piperidine se nkeloang sebaka ke sehlopha sa benzyl athomong ea naetrojene le sehlopha sa propyl athomong ea carbon. Motsoako ona o tsositse thahasello k'hemistring ea meriana ka lebaka la ho rarahana ha sebopeho sa oona le ts'ebeliso e ka bang teng ea meriana. Tokisetso ea oona e ikhethang e fana ka menyetla ea ho rala bakhethoa ba meriana ba bacha ba nang le lipheo tse itseng tsa baeloji, e leng se etsang hore e be letlotlo la bohlokoa boitekong ba ho sibolla lithethefatsi le nts'etsopele.
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9,9-Dimethyl-9H-fluoren-2-yl-boronic acid CAS:333432-28-3
9,9-Dimethyl-9H-fluoren-2-yl-boronic acid, eo hangata e bitsoang DMFBA, ke motsoako oa lik'hemik'hale o leng sehlopheng sa li-acid tsa boronic. Sebopeho sa eona sa limolek'hule se na le karolo ea boronic acid e hoketsoeng ho scaffold ea fluorene e nkeloang sebaka ke lihlopha tse peli tsa methyl sebakeng sa 9. Motsoako ona o na le bohlokoa bo boholo tlhahisong ea lintho tse phelang, haholo-holo liketsong tsa ho kopanya tsa Suzuki-Miyaura, moo o sebetsang e le reagent ea boronic acid e feto-fetohang. Ho feta moo, sebopeho sa eona se tiileng le se sitisitsoeng ke sterility se etsa hore e be ea bohlokoa moralong oa ligand bakeng sa liketso tse fetotsoeng tsa tšepe le nts'etsopele ea thepa e sebetsang.
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4-Carboxyphenylboronic acid CAS: 14047-29-1
4-Carboxyphenylboronic acid, e tsejoang hape e le 4-Carboxyphenylboronic acid kapa 4-CPBA, ke motsoako oa lik'hemik'hale o leng sehlopheng sa li-acid tsa boronic. E khetholloa ka sehlopha sa eona sa boronic acid functional (-B(OH)₂) se hoketsoeng lesale la phenyl le nkeloang sebaka ke sehlopha sa carboxylic acid (-COOH) boemong ba para. Motsoako ona o fumana ts'ebeliso e pharaletseng ho organic synthesis, haholo-holo liketsong tsa ho kopanya Suzuki-Miyaura ho theha litlamo tsa carbon-carbon. Ho feta moo, bokhoni ba eona ba ho tlamahana le diols le tsoekere bo lebisitse tšebelisong ea eona nts'etsopele ea li-sensor bakeng sa ho lekola tsoekere le k'hemistri ea meriana bakeng sa ho rala li-enzyme inhibitors le li-receptor ligands.
