Diethylacetamidomalonate CAS:1068-90-2

Diethylacetamidomalonate e sebelisoa haholo k'hemistring ea lintho tse phelang e le motheo oa ho kopanya metsoako ea heterocyclic, meriana, lik'hemik'hale tsa temo le lihlahisoa tsa tlhaho tse rarahaneng. E sebetsa e le selelekela sa bohlokoa tlhahisong ea pyrazoles, pyridine, le metsoako e meng e nang le naetrojene e nang le mesebetsi ea baeloji. Ho feto-fetoha ha diethylacetamidomalonate ho lumella litsebi tsa lik'hemistri ho hlahisa lihlopha tse fapaneng tsa ts'ebetso le likarolo tsa stereochemical ka har'a limolek'hule, ho nolofalletsa ho hlahloba meaho e mecha ka lits'ebetso tse ka bang teng tsa kalafo. Phuputsong ea meriana, diethylacetamidomalonate e sebelisoa ho rala le ho kopanya bakhethoa ba lithethefatsi ba shebaneng le mafu a fapaneng a kang mofetše, mafu a tšoaetsanoang le mathata a methapo ea kutlo. Bokhoni ba eona ba ho feta mefuteng e mengata ea liketso bo e etsa hore e be sethala sa bohlokoa sa ho theha lilaebrari tsa limolek'hule bakeng sa tlhahlobo e phahameng ea phallo le ntlafatso ea loto mananeong a ho sibolla lithethefatsi. Ho feta moo, boteng ba ts'ebetso ea ester le amide ho diethylacetamidomalonate bo fana ka menyetla ea ho fetola thepa ea pharmacokinetic le ho ntlafatsa matla a lithethefatsi le khetho. Ka kakaretso, ditshebediso tse fapaneng tsa diethylacetamidomalonate tlhahisong ya dintho tse phelang le ntshetsopeleng ya dithethefatsi di totobatsa bohlokwa ba yona ho ntshetseng pele tsebo ya mahlale le ho kenya letsoho ho sibollweng ha dikalafo tse ntjha tse nang le bokgoni bo ntlafetseng le diprofayili tsa polokeho.