Dehydrogenase, joala CAS: 9031-72-5 Theko ea moetsi

Li-dehydrogenase ke sehlopha sa li-enzyme tse susumetsang oxidation ea substrate ka ho tlosa liathomo tsa haedrojene. Ha ho tluoa tabeng ea dehydrogenase ea joala, e sebetsa ka ho khetheha ho li-alcohol, e nolofalletsa phetoho ea tsona ho ba li-aldehyde kapa li-ketone ka ho tlosa liathomo tsa haedrojene.

Mabapi le phello ea joala, dehydrogenase ea joala e bapala karolo ea bohlokoa ho metabolism ea ethanol 'meleng oa motho. E thusa ho qhaqha ethanol hore e be acetaldehyde, e ntan'o fetoloa hore e be acetic acid. Ts'ebetso ena e bohlokoa ho thibeleng ho bokellana ha maemo a chefo a ethanol 'meleng. Leha ho le joalo, ho noa joala ho feteletseng ho ka imela bokhoni ba dehydrogenase ea joala, e leng se fellang ka ho bokellana ha acetaldehyde, e amanang le matšoao a sa thabiseng a tsejoang e le karabelo ea alcohol flush.

Mabapi le tshebediso, alcohol dehydrogenase e na le tshebediso tse mmalwa tsa bohlokwa. E sebediswa hangata tlhahisong ya ethanol indastering ya ho bedisa. Enzyme ena e sebediswa ho susumetsa phetoho ya tswekere ho ba ethanol ke tomoso kapa dibaktheria. Ho feta moo, alcohol dehydrogenase e sebediswa mekgweng e fapaneng ya laboratori le ditekong tsa tlhahlobo. E sebediswa ho lekanya maemo a jwala ditekong tsa breathalyzer le ditekong tsa joala mading (BAC). Ho feta moo, e fumana tshebediso tlhahisong ya dikhemikhale, tse kang di-organic acid le di-ester, ka ditshebetso tsa biocatalysis.