Boc-Leu-ONp CAS:3350-19-4

Boc-Leu-ONp e sebelisoa haholo mawa a ho kopanya di-bio le mekgwa ya ho fetola di-peptide. Ho kopantsweng ha di-peptide, ho nolofalletsa ho kenngwa ha masalla a leucine ka taolong ya di-peptide, ho dumella ho hokelwa ha dihlopha tse fapaneng tse sebetsang, di-label, kapa dimolek'hule bakeng sa ditshebediso tse fapaneng. Phetoho ena e kgethilweng e thusa ho thehwa ha di-peptide tse sebetsang ka bongata tse nang le thepa e ikgethileng, jwalo ka botsitso bo ntlafetseng, ho ikgetha ha sepheo, kapa bokgoni ba ho nka ditshwantsho. Phuputsong ya proteomics, Boc-Leu-ONp e dumella ho ngolwa ha diprotheine le di-peptide ka ho ikgetha sebakeng seo, ho kenya letsoho tlhahlobong ya sebopeho, dithutong tsa tshebedisano, le ditekong tse thehilweng ho mass spectrometry. Ho hokelwa ho laolwang ha Boc-Leu-ONp ho masalla a leucine ho nolofalletsa ho hlaloswa ka nepo le tlhahlobo ya tshebetso ya diprotheine le di-peptide, ho tshehetsa kgatelopele ya ho utlwisisa ditsamaiso tsa baeloji le mekgwa ya mafu. Ho feta moo, ntshetsopeleng ya dithethefatsi, Boc-Leu-ONp e bapala karolo ya bohlokwa ho kopanyeng di-agent tsa kalafo le di-peptide kapa diprotheine, ho theha ditsamaiso tsa ho fana ka dithethefatsi tse reretsweng, di-conjugate tsa di-antibody-drug, kapa meaho ya diente e nang le diprofaele tse ntlafetseng tsa pharmacokinetic le ditlamorao tse fokotsehileng tse sa rerelwang. Ka bokhutšoanyane, botšepehi le ho tenyetseha ha Boc-Leu-ONp phetohong ea peptide le ho kopanngoa ha lintho tse phelang ho e etsa sesebelisoa sa bohlokoa bakeng sa ho ntšetsa pele lipatlisiso tsa ho sibolloa ha lithethefatsi, baeloji ea lik'hemik'hale le li-proteomics, e fanang ka menyetla e fapaneng ea ho nts'etsapele lits'ebetso tse ncha tsa bongaka.