Bethahistinemethanesulfonate CAS: 54856-23-4

Bethahistinemethanesulfonate e sebelisoa haholo lefapheng la bongaka, haholo-holo bakeng sa melemo ea eona ea kalafo ho phekoleng mathata a vestibular a kang lefu la Meniere le maemo a mang a amanang le botsitso. Lefu la Meniere le kenyelletsa liketsahalo tsa vertigo, tinnitus, le tahlehelo ea kutlo, tse bakoang ke ho se tloaelehe ha metsi tsebeng e ka hare. Tsamaiso ea Bethahistinemethanesulfonate e ka thusa ho fokotsa matšoao ana ka ho ntlafatsa phallo ea mali ho ea ka hare tsebeng, ka hona ho tsitsisa tsamaiso ea vestibular le ho fokotsa makhetlo le boima ba liketsahalo tse vertiginous. Ntle le mathata a vestibular, Bethahistinemethanesulfonate e ka boela ea ba molemo ho phekoleng maemo a mang a amanang le ho fokola ha phallo ea mali. Ka ho sebetsa e le vasodilator, e thusa ho ntlafatsa phallo ea mali liseleng tse fapaneng, e leng se etsang hore e be molemo ho bakuli ba nang le mafu a methapo ea mali. Ntlafatso ena ea phallo ea mali e ka ntlafatsa phepelo ea oksijene le limatlafatsi libakeng tse amehileng, e khothalletsa pholiso le ts'ebetso e betere. Ho feta moo, lipatlisiso li bontšitse lits'ebetso tse ka bang teng tsa Bethahistinemethanesulfonate ts'ireletsong ea methapo le ntlafatsong ea kelello. Tšebetso ea eona e le agonist ea histamine receptor e bontša hore e ka bapala karolo ho fetoleng ho lokolloa ha li-neurotransmitter, ka hona e susumetsa lits'ebetso tsa kelello le ho fana ka litlamorao tsa ts'ireletso ea methapo mafung a methapo ea kutlo. Motsoako ona o ka boela oa nahanoa bakeng sa ts'ebeliso maemong a mang, joalo ka kalafong ea litlamorao tse itseng tsa allergy ka lebaka la ts'ebetso ea eona ea histamine. Leha ho le joalo, ts'ebeliso ea eona sebakeng sena e hloka lipatlisiso tse ling le netefatso. Ka kakaretso, Bethahistinemethanesulfonate ke moemeli oa phekolo o feto-fetohang o tsejoang ka litlamorao tsa ona tse ntle ts'ebetsong ea vestibular le phallo ea mali, o bontša tšepiso lits'ebetsong tse fapaneng tsa bongaka tse shebaneng le ho ntlafatsa boleng ba bophelo ba mokuli.