beta-Nicotinamide adenine dinucleotide trihydrate CAS:53-84-9

Tlhahiso ea matla: β-NAD+ ke karolo ea bohlokoa ts'ebetsong ea ho fetola lijo hore e be matla. E sebetsa e le coenzyme ho phefumoloheng ha sele, e nolofalletsang phetisetso ea lielektrone ho tloha ho metabolites ho ea ketane ea lipalangoang tsa lielektrone. Phetisetso ena ea lielektrone e bohlokoa bakeng sa tlhahiso ea ATP, e leng chelete e ka sehloohong ea matla a lisele.

Tokiso ea DNA: β-NAD+ e ameha lits'ebetsong tsa tokiso ea DNA. E sebetsa e le substrate bakeng sa lienzyme tse kang PARPs (Poly [ADP-ribose] polymerases), tse sebelisang β-NAD+ ho lokisa DNA e senyehileng ho arabela likhatellong tse fapaneng tsa sele tse kang tšenyo ea DNA e bakoang ke mahlaseli a kotsi, chefo, kapa khatello ea oxidative.

Ho supa lisele: β-NAD+ e hlahile e le molek'hule ea bohlokoa ea ho supa e amehang litseleng tse fapaneng tsa sele. E ka sebetsa e le selelekela sa limolek'hule tse fapaneng tsa ho supa, joalo ka ADP-ribose ea cyclic le NAADP, tse laolang ho lokolloa ha calcium le phetisetso ea matšoao. Ho feta moo, metabolism ea β-NAD+ e ka susumetsa tlhahiso ea liphatsa tsa lefutso, botsofali le lits'ebetso tse ling tsa 'mele.

Mekhoa ea phekolo: Ho ntse ho fuputsoa tlatsetso ea β-NAD+ le phetoho ea maemo a β-NAD+ bakeng sa mekhoa e ka bang teng ea phekolo. Lithuto tsa morao tjena li bontša hore ho eketsa maemo a β-NAD+ ho ka ba le liphello tse molemo mafung a amanang le botsofali, mathata a methapo ea kutlo, mathata a metabolism, le bophelo bo botle ba pelo le methapo. Ho boetse ho na le lipatlisiso tse tsoelang pele mabapi le tšebeliso ea lintho tse etellang pele tsa β-NAD+, tse kang nicotinamide riboside le nicotinamide mononucleotide, e le litlatsetso tse ka bang teng tsa ho eketsa maemo a β-NAD+ 'meleng.