4-bromo-2,3-dihydro-1H-inden-1-ol 4CAS:16657-10-6

4-bromo-2,3-dihydro-1H-inden-1-ol e bapala karolo ea bohlokoa e le mokena-lipakeng oa metsoako e rarahaneng, e sebetsang 'meleng e nang le lits'ebetso tse ka bang teng tsa meriana. Ho kenyelletsoa ha eona meralong ea limolek'hule ho nolofalletsa bafuputsi ho hlahloba bakhethoa ba bacha ba meriana ba shebaneng le libaka tsa kalafo tse kang mathata a methapo ea kutlo, oncology, kapa ho ruruha. Phetoho ea bromo e hlahisa reactivity e itseng le thepa ea pharmacophoric, e leng se etsang hore e be ea bohlokoa bakeng sa lipatlisiso tsa k'hemistri ea meriana. Maitekong a ho sibolla lithethefatsi, motsoako ona o ka sebetsa e le sebaka sa ho qala ho rala bakhethoa ba meriana ba ka bang teng, o sebelisa likarolo tsa oona tsa sebopeho ho fetola ts'ebetso ea baeloji le thepa ea pharmacokinetic. Ho feta moo, karolo ea eona ea mantlha ea dihydroindenol e fana ka sethala se ikhethang bakeng sa nts'etsopele ea likarolo tse fapaneng tsa lik'hemik'hale tse nang le bohlokoa bo ka bang teng ba kalafo. Ho feta moo, libakeng tsa thuto le tsa indasteri, bafuputsi ba ka sebelisa motheo ona ho lokisa lilaebrari tsa lintho tse fapaneng tse tsoang ho tsona bakeng sa lithuto tsa kamano ea sebopeho le ts'ebetso, ho nolofalletsa ho tsebahatsa metsoako ea loto e nang le litlamorao tse lakatsehang tsa baeloji. Karolo ea eona ho kopanyeng lik'hemik'hale e atoloha ho tlhahiso ea li-intermediate tsa meriana le nts'etsopele ea mekhoa e mecha ea maiketsetso, e bonts'a thuso ea eona e pharaletseng mafapheng a saense. Ka kakaretso, 4-bromo-2,3-dihydro-1H-inden-1-ol e bapala karolo ea bohlokoa ho phehelleng ho sibolloa ha meriana e mecha le lipatlisiso tsa lik'hemik'hale, e fana ka sethala sa nts'etsopele ea limolek'hule tse fapaneng tse sebetsang ka baeloji le metsoako e mahareng ea meriana.