3-amino-6-hydroxypicolinic acid CAS:1269291-72-6

Asiti ea 3-amino-6-hydroxypicolinic e na le thuso e kholo lipatlisisong tsa meriana le tlhahiso ea lintho tse phelang. Tšebeliso e 'ngoe ea mantlha ke karolo ea eona e le karolo ea bohlokoa ea ho lokisa metsoako e sebetsang ka baeloji le metsoako ea meriana. Ka ho sebelisa likarolo tsa eona tsa sebopeho le karabelo, bafuputsi ba ka sebelisa motsoako ona ho fumana metsoako e fapaneng e nang le mesebetsi e ka bang teng ea meriana, e tlatsetsang nts'etsopele ea meriana e mecha le metsoako ea phekolo. Ho feta moo, motsoako ona o sebetsa e le thepa ea bohlokoa ea ho qala bakeng sa tlhahiso ea limolek'hule tse rarahaneng tse nang le bohlokoa ba baeloji. Ka lihlopha tsa eona tse sebetsang, e ka nka karolo liketsong tse fapaneng tsa tlhaho, e nolofalletsang kaho ea li-scaffolds tse fapaneng tsa limolek'hule bakeng sa ho hlahloba haholoanyane likamano tsa sebopeho le ts'ebetso le bakhethoa ba meriana ba ka bang teng. Ho feta moo, asiti ea 3-amino-6-hydroxypicolinic e ka fumana ts'ebeliso e le motheo oa ho kopanya li-ligand tse shebaneng le lipheo tse itseng tsa baeloji tse kang li-receptor kapa li-enzyme. Sena se lumella nts'etsopele ea metsoako bakeng sa ho ithuta litsela tsa biochemical le likamano, ka hona ho atolosa ts'ebeliso ea eona boitekong ba ho sibolla lithethefatsi le ho hlakisa mekhoa ea baeloji. Ka bokhutšoanyane, ho tenyetseha ha motsoako ona ho o etsa letlotlo la bohlokoa lipatlisisong tsa meriana, ho fana ka bokhoni ba ho theha limolek'hule tse fapaneng tse nang le mesebetsi e ka bang teng ea phekolo le ho kenya letsoho ho ntšetseng pele ho sibolloa ha meriana le boiteko ba nts'etsopele.