(2S,4R)-4-aMinopyrrolidine-2-carboxylic acid hydrochloride CAS:16257-89-9

(2S,4R)-4-aminopyrrolidine-2-carboxylic acid hydrochloride e bapala karolo ea bohlokoa lipatlisisong le nts'etsopele ea meriana, e sebetsa e le motheo oa bohlokoa bakeng sa ho lokisa li-peptide tse rarahaneng le li-peptidomimetics tse nang le mesebetsi e fapaneng ea bio le bokhoni ba kalafo. Ho kenyelletsoa ha eona ka har'a liketane tsa peptide ho thusa ho theha metsoako e amanang le meriana, ho kenyeletsoa lihormone tsa peptide, li-enzyme inhibitors, le bakhethoa ba lithethefatsi, ka hona ho kenya letsoho nts'etsopele ea mekhoa e mecha ea kalafo bakeng sa maemo a fapaneng a bongaka. Ho feta moo, motsoako ona o sebelisoa ho synthesis ea peptide ea mohato o tiileng (SPPS), o nolofalletsang kopano e sebetsang le e laoloang ea tatellano ea li-peptide tse rarahaneng. Ho lumellana ha eona le mekhoa ea SPPS ho lumella tlhahiso ea li-peptide tse ikhethileng le lilaebrari tsa peptide tse sebelisoang lithutong tsa baeloji, tlhahlobo ea lithethefatsi le lipatlisiso tsa biochemical, ho bonts'a karolo ea eona ea bohlokoa ho ntšetseng pele mahlale a thehiloeng ho peptide. Ho feta moo, (2S,4R)-4-aminopyrrolidine-2-carboxylic acid hydrochloride e sebelisoa lilaboratoring tsa thuto le tsa indasteri bakeng sa ho batlisisa reactivity ea peptide, likamano tsa sebopeho le mosebetsi, le maano a phetoho ea peptide, ho tšehetsa tsoelo-pele k'hemistri ea peptide le ho sibolloa ha lithethefatsi. Tšebeliso e nang le mahlakore a mangata ea (2S,4R)-4-aminopyrrolidine-2-carboxylic acid hydrochloride e totobatsa karolo ea eona ea bohlokoa lipatlisisong tsa peptide, tlhahiso ea meriana, le nts'etsopele ea mekhoa ea phekolo e thehiloeng ho peptide, e leng se susumetsang tsoelo-pele theknolojing ea baeloji le k'hemistri ea meriana.