(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid CAS:132622-69-6

(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid e sebetsa e le motheo oa bohlokoa tlhahisong ea li-peptide le li-peptidomimetics tse nang le mesebetsi e fapaneng ea bio le bokhoni ba kalafo. Ho kenyelletsoa ha eona ka har'a liketane tsa peptide ho thusa ho thehoa ha metsoako e amanang le meriana, ho kenyeletsoa lihormone tsa peptide, li-enzyme inhibitors, le ba ka bang teng ba ka nkang meriana. Ho phaella moo, motsoako ona o sebelisoa ho lokiseng meriana e thehiloeng ho peptide bakeng sa lipatlisiso, tlhahlobo le kalafo, e tlatsetsang nts'etsopele ea mekhoa e mecha ea phekolo bakeng sa maemo a fapaneng a bongaka. Ho feta moo, (2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid e sebelisoa haholo ho synthesis ea peptide ea mohato o tiileng (SPPS), e nolofalletsang kopano e sebetsang hantle le e laoloang ea tatellano e rarahaneng ea li-peptide. Ho lumellana ha eona le mekhoa ea SPPS ho lumella tlhahiso ea li-peptide tse ikhethileng le lilaebrari tsa peptide tse sebelisoang lithutong tsa baeloji, tlhahlobo ea lithethefatsi le lipatlisiso tsa biochemical, e totobatsang karolo ea eona ea bohlokoa ho ntšetseng pele mahlale a thehiloeng ho peptide. Ho feta moo, motsoako ona o sebediswa dilaboratoring tsa thuto le tsa indasteri bakeng sa ho batlisisa ka moo peptide e sebetsang ka teng, dikamano tsa sebopeho le mosebetsi, le mawa a phetoho ya peptide, ho tshehetsa kgatelopele k'hemistring ya peptide le ho sibollwa ha dithethefatsi. Ka kakaretso, tshebediso e nang le mahlakore a mangata ya (2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid e totobatsa karolo ya yona ya bohlokwa dipatlisisong tsa peptide, tlhahisong ya meriana, le ntshetsopeleng ya kalafo e thehilweng ho peptide, e kgannang kgatelopele ho theknoloji ya baeloji le k'hemistri ya meriana.