2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS:86520-63-0

2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate ke motsoako oa lik'hemik'hale o atisang ho sebelisoa lik'hemik'hale tsa lik'hemik'hale tsa lik'hemik'hale le glycosylation reactions.E tsoa ho α-D-galactopyranose, mofuta oa tsoekere, moo lihlopha tsa hydroxyl tse maemong a 2, 3, 4, le 6 a selikalikoe sa galactopyranose li nang le acetylated.Ho phaella moo, anomeric carbon (C1) ea tsoekere e sirelelitsoe ka sehlopha sa trichloroacetimidate, se etsang hore e be electrophile e matla nakong ea liketso tsa glycosylation.

Hangata motsoako ona o sebelisoa e le glycosylating agent ho hlahisa likarolo tsa galactose ka limolek'hule tse sa tšoaneng, tse kang liprotheine, li-peptide kapa limolek'hule tse nyenyane tsa tlhaho.Sena se ka finyelloa ka ho sebetsana le motsoako ona ka nucleophile (mohlala, lihlopha tsa hydroxyl holim'a molek'hule e reretsoeng) tlas'a maemo a loketseng.Sehlopha sa trichloroacetimidate se thusa ho khomarela karolo ea galactose ho molek'hule e lebisitsoeng, e leng se etsang hore ho thehoe tlamo ea glycosidic.

Motsoako ona o atisa ho sebelisoa ha ho etsoa glycoconjugates, glycopeptides le glycolipids.E fana ka mokhoa o feto-fetohang le o sebetsang oa ho fetola limolek'hule tse nang le masalla a galactose, tse ka sebetsang mafapheng a fapaneng, ho kenyeletsoa lithuto tsa baeloji, lits'ebetso tsa phano ea lithethefatsi, kapa nts'etsopele ea ente.

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Glycosylation: Motsoako o sebetsana le limolek'hule tse fapaneng tse amohelang tse nang le lihlopha tsa hydroxyl, joalo ka lino tse tahang kapa li-amine, ho theha bond ea glycosidic.Sena se lumella ho kenngoa ha galactose ho molek'hule e amohelang, e leng se etsang hore ho be le motsoako oa li-glyccoconjugates, glycopeptides, kapa glycolipids.

Lithuto tsa biochemical le tsa baeloji: Motsoako ona o thusa bafuputsi ho ithuta mesebetsi ea tlhaho le tšebelisano ea limolek'hule tse nang le galactose.Ka ho khetha ho hokela galactose ho liprotheine, li-peptide, kapa li-biomolecules tse ling, bafuputsi ba ka batlisisa karolo ea bona lits'ebetsong tsa cellular, litšebelisano tsa li-receptor-ligand le mekhoa ea mafu.

Sistimi ea phepelo ea lithethefatsi: Motsoako ona o ka sebelisoa ho fetola limolek'hule tsa lithethefatsi ka mesaletsa ea galactose, ho nolofatsa phepelo ea lithethefatsi tse lebisitsoeng ho lisele kapa lisele tse itseng.Galactose e ka sebetsa joalo ka ligand e lebisitseng tlhokomelo, e lemoha li-receptor tse khethehileng tse hlahisoang holim'a lisele, haholo-holo li-hepatocyte.Ka ho hokela galactose ho lithethefatsi, bafuputsi ba ka ntlafatsa khetho ea bona le katleho ea bona kalafong e lebisitsoeng.

Nts'etsopele ea ente: Limolek'hule tse nang le galactose li bapala karolo ea bohlokoa karabelong ea 'mele ea ho itšireletsa mafung, kaha li bonoa ke li-lectins tse teng liseleng tsa 'mele.Ka ho kopanya li-antigen le likarolo tsa galactose ba sebelisa motsoako ona, bafuputsi ba ka ntlafatsa likarabo tsa 'mele oa ho itšireletsa mafung le ho hlahisa liente tse sebetsang hantle.

Motsoako oa lik'hemik'hale: Motsoako o ka sebelisoa mefuteng e fapaneng ea lik'hemik'hale moo ho hlokahalang liphetoho tsa galactose.Sena se kenyelletsa ho lokisoa ha metsoako e rarahaneng ea lik'habohaedreite, li-oligosaccharides, kapa glycomimetics, tse ka sebelisoang ho feta k'hemistri ea meriana kapa e le lisebelisoa tsa lipatlisiso.

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Tlhahisoleseling e 'Ngoe:

Sebopeho	C16H20Cl3NO10
Tlhahlobo	99%
Ponahalo	Phofo e tšoeu
Nomoro ea CAS.	86520-63-0
Ho paka	Tse nyenyane le tse ngata
Shelf Life	lilemo tse 2
Polokelo	Boloka sebakeng se phodileng le se omileng
Setifikeiti	ISO.