2-Chloroethylaminehydrochloride CAS: 870-24-6

2-Chloroethylamine hydrochloride e na le lits'ebetso tse fapaneng tsa bohlokoa masimong a k'hemistri, pharmacology le biotechnology. E 'ngoe ea ts'ebeliso ea eona ea mantlha ke ho ba moemeli oa alkylating ho kopanyeng metsoako ea meriana le metsoako e sebetsang ka baeloji. Ka ho hlahisa sehlopha sa 2-chloroethylamine ka limolek'hule, litsebi tsa k'hemistri li ka fetola thepa ea tsona le ho ntlafatsa mesebetsi ea tsona ea baeloji bakeng sa merero ea bongaka. Ntle le karolo ea eona nts'etsopele ea lithethefatsi, 2-Chloroethylamine hydrochloride e sebelisoa lipatlisisong tsa mofetše le chemotherapy e le selelekela sa mosetareta oa naetrojene. Lisebelisoa tsena tsa alkylating ke likarolo tsa bohlokoa tsa mekhoa e itseng ea chemotherapy bakeng sa ho phekola mefuta e fapaneng ea mofetše. Ka ho sebelisa thepa ea alkylating ea 2-Chloroethylamine hydrochloride, bafuputsi ba ikemiselitse ho sitisa karohano ea sele le ho baka apoptosis liseleng tsa mofetše, qetellong ho thibela kholo ea hlahala le metastasis. Ho feta moo, motsoako ona o sebelisoa lithutong tsa biochemical ho batlisisa likarabelo tsa alkylation, mekhoa ea tšenyo ea DNA le liphetoho tsa protheine. Bo-rasaense ba sebelisa 2-Chloroethylamine hydrochloride e le sesebelisoa sa ho utloisisa liphello tsa limolek'hule tsa li-alkylating agents ho li-biomolecule le lits'ebetso tsa sele, e leng se fanang ka leseli ka mekhoa ea ts'ebetso ea meriana e loantšang mofetše le lipheo tse ka bang teng bakeng sa ho kenella kalafong. Ho feta moo, 2-Chloroethylamine hydrochloride e sebetsa e le reagent ea bohlokoa liphetohong tsa tlhaho, ho kenyeletsoa le ho kopanngoa ha metsoako ea heterocyclic, li-amino derivatives, le limolek'hule tse sebetsang. Ho sebetsana ha eona ka mekhoa e mengata le bokhoni ba alkylation bo khethang bo nolofalletsa litsebi tsa lik'hemik'hale ho fumana meaho e fapaneng ea lik'hemik'hale e nang le thepa le lits'ebetso tse itseng meriana, saense ea thepa le baeloji ea lik'hemik'hale. Ka kakaretso, 2-Chloroethylamine hydrochloride e bapala karolo ea bohlokoa ho sibolloeng ha lithethefatsi, kalafo ea mofetše, tlhahiso ea lik'hemik'hale le lipatlisiso tsa biochemical, e bonts'a ho feto-fetoha ha eona le bohlokoa ba eona ho ntšetseng pele tsebo ea mahlale, mekhoa ea kalafo ea bongaka le boqapi ba lik'hemik'hale. Thepa ea eona ea alkylamine le likamano tsa limolek'hule li fana ka temohisiso ea bohlokoa mabapi le ho rala metsoako e mecha, ho utloisisa mekhoa ea mafu, le ho nts'etsapele mekhoa e reretsoeng ho sebetsana le liphephetso tse rarahaneng tsa bongaka.