1,1,1,3,3,3-Hexafluoro-2-propanol CAS:920-66-1

1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP) ke motsoako o feto-fetohang o nang le litšobotsi tse ikhethang tsa lik'hemik'hale tse etsang hore e be ea bohlokoa lits'ebetsong tse fapaneng tsa indasteri. Thepa HFIP e khetholloa ka sebopeho sa eona sa limolek'hule, e nang le khabone e phahameng e hokahaneng le sehlopha sa hydroxyl (-OH) 'me e pota-potiloe ke liathomo tse tšeletseng tsa fluorine. Tokisetso ena e fana ka botsitso bo ikhethang le boemo bo phahameng ba fluorination, e tlatsetsang litšobotsing tsa eona tse ikhethang tsa solvent. HFIP ke mokelikeli o hlakileng, o se nang 'mala o nang le ntlha e belang ea hoo e ka bang 58°C mme o bontša ho qhibiliha ho hoholo ho li-solvent tsa polar le tse seng polar. Bokhoni ba eona bo matla ba ho kopanya hydrogen bo e etsa hore e be solvent e sebetsang bakeng sa metsoako ea polar, ho kenyeletsoa liprotheine le li-nucleic acid, 'me e ntlafatsa ts'ebeliso ea eona e le stabilizer ho li-formations tse hlokang libaka tse sa sebetseng le tse sa sebetseng. E Sebelisa Solvent ho Organic Synthesis: HFIP e sebelisoa haholo e le solvent k'hemistri ea organic, haholo-holo bakeng sa ho qhibiliha le karabelo ea metsoako e nang le fluorine e ngata. Bokhoni ba eona ba ho tsitsisa metsoako e arabelang le ho ntlafatsa sekhahla sa karabelo bo e etsa hore e be ea bohlokoa haholo tlhahisong ea meriana, lik'hemik'hale tsa temo le lik'hemik'hale tse ikhethang tse hlokang taolo e nepahetseng maemong a karabelo. Khemistri ea Polymer: Saenseng ea polymer, HFIP e sebetsa e le tharollo bakeng sa ho qhibiliha le ho fetoloa ha li-polymer tse nang le fluorine, tse kang polytetrafluoroethylene (PTFE) le polyvinylidene fluoride (PVDF). E nolofalletsa ts'ebetso ea lisebelisoa tsena hore e be lifilimi, likhoele le lipente tse nang le botsitso bo matlafalitsoeng le khanyetso ea lik'hemik'hale. Litšebeliso tsa Biomedical: HFIP e fumana lits'ebetso lipatlisisong tsa biomedical le mekhoa ea meriana ka lebaka la bokhoni ba eona ba ho qhala liprotheine le li-peptide ha e ntse e boloka meaho ea tsona ea tlhaho. E sebelisoa ho lokiseng lintho tsa tlhaho, litsamaiso tsa ho fana ka lithethefatsi, le e le stabilizer lienteng le li-reagent tsa tlhahlobo. Ho kopanya HFIP e ka etsoa ka mekhoa e 'maloa, ho kenyeletsoa karabelo ea hexafluoropropylene ka metsi tlas'a maemo a laoloang kapa hydrolysis ea hexafluoroacetone. Mokhoa oa morao-rao o kenyelletsa kalafo ea hexafluoroacetone ka metsi le catalyst e loketseng ea acid ho hlahisa HFIP e le sehlahisoa se seholo. Mekhoa ea ho hloekisa e kang ho qhibilihisa kapa ho ntša solvent e sebelisoa ho fumana HFIP e hloekile haholo e loketseng lits'ebetso tsa indasteri le tsa laboratori. Ka bokhutšoanyane, 1,1,1,3,3,3-hexafluoro-2-propanol ke motsoako o feto-fetohang o nang le lits'ebetso tsa bohlokoa tlhahisong ea lintho tse phelang, k'hemistri ea polymer, le lipatlisiso tsa bongaka. Thepa ea eona e ikhethang ea lik'hemik'hale, ho kenyeletsoa fluorination e phahameng, bokhoni bo matla ba ho kopanya hydrogen, le katleho ea solvent, e nolofalletsa tšebeliso ea eona e pharaletseng makaleng a fapaneng a indasteri, e tlatsetsa tsoelo-peleng ea saense ea thepa, meriana le mahlale a lik'hemik'hale.