Letrozole CAS:112809-51-5 Moetsi oa Moetsi Setšoantšo se Hlahelitsoeng

Letrozole CAS:112809-51-5 Mofani oa Moetsi

Letrozole ke karolo ea moloko o mocha oa li-aromatase inhibitors tse khethang haholo 'me ke motsoako oa maiketsetso oa benzotriazole.Letrozole e thibela aromatase ho theola maemo a estrogen, kahoo e thibela estrogen ho susumetsa kholo ea hlahala.Ts'ebetso ea eona ea in vivo e matla ka makhetlo a 150-250 ho feta ea moloko oa pele oa aromatase inhibitor Amarante.Kaha e khetha haholo, e ke ke ea ama glucocorticoid, mineralocorticoid le mesebetsi ea qoqotho;esita le ka litekanyetso tse phahameng, e ke ke ea e-ba le liphello tse thibelang li-adrenal corticosteroid secretion, e fanang ka index e phahameng ea phekolo.

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Letrazole e ka etsoa ka mehato e 'meli ho tloha 4- bromomethyl-benzonitrile le 1,2,4-triazole' me ke moloko oa boraro oa aromatase inhibitor.Ke inhibitor e khethehileng haholo ea P450arom e thibelang phetoho ea androstenedione ho estrone.Phokotso ea plasma estrogen e bile hang-hang ebile e tšoarella nako e telele.Sena se finyelloa ntle le thibelo ea steroid biosynthesis e etsang hore e be eona e khethehileng ka ho fetisisa ea aromatase inhibitor e lekiloeng.Letrazole e na le ts'ebetso e tsotehang ea antitumor, e mamelloa hantle ebile ha e na litla-morao tse chefo.E matla ho feta aminoglutethimide ka makhetlo a 10,000, ka vivo, e leng ea pele e thehiloeng hantle ea aromatase inhibitor.

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Tlhahisoleseling e 'Ngoe:

Sebopeho	C17H11N5
Tlhahlobo	99%
Ponahalo	Phofo e tšoeu
Nomoro ea CAS.	112809-51-5
Ho paka	25KG
Shelf Life	lilemo tse 2
Polokelo	Boloka sebakeng se phodileng le se omileng
Setifikeiti	ISO.